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Deltex Homolog 1

Known as: Deltex-1, Deltex Protein 1, hDTX1 
Deltex Homolog 1, encoded by the human DTX1 gene, is a transcription corepressor. Notch1 activates CSL by displacing corerepssors and recruiting… 
National Institutes of Health

Related topics

Related topics

10 relations
DTX1 geneHomo sapiensNotch Signaling PathwayRing Finger Domain

Papers overview

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2020
2020
Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis
Deltex‐1 (DTX1) is a negative regulator of the Notch signaling pathway. Here, we investigated the clinical effect of DTX1… 
2019
2019
Deltex1 suppresses T cell function and is a biomarker for diagnosis and disease activity of systemic lupus erythematosus
OBJECTIVE Deletion of Deltex1 (DTX1) in mice caused hyperactivation of T cells and lupus-like autoimmune syndromes, however, the… 
2019
2019
Deltex1 suppresses T cell function and is a biomarker for diagnosis and disease activity of systemic lupus erythematosus.
OBJECTIVE Deletion of Deltex1 (DTX1) in mice caused hyperactivation of T cells and lupus-like autoimmune syndromes, however, the… 
2018
2018
In Vivo MR Imaging of Dual MRI Reporter Genes and Deltex-1 Gene-modified Human Mesenchymal Stem Cells in the Treatment of Closed Penile Fracture
PurposeThe purpose of this study was to investigate the feasibility of dual magnetic resonance imaging (MRI) reporter genes… 
2018
2018
Effect of Deltex-1 on proliferation and differentiation of bone marrow mesenchymal stem cells into smooth muscle cells.
OBJECTIVE To investigate the effect of Deltex-1 on proliferation and differentiation of bone marrow mesenchymal stem cells (bMSCs… 
2016
2016
Aberrant expression of Notch1, HES1, and DTX1 genes in glioblastoma formalin-fixed paraffin-embedded tissues
Glioblastoma is the most common malignant brain tumor accounting for more than 54 % of all gliomas. Despite aggressive treatments… 
2013
2013
Jagged-1-HES-1 signaling inhibits the differentiation of TH17 cells via ROR gammat.
Notch signaling plays an important role in differentiation of T cells. However, little is known as to action of it in… 
2008
2008
Notch induces cell cycle arrest and apoptosis in human erythroleukaemic TF-1 cells.
2005
2005
OLIG 2 ( BHLHB 1 ) , a bHLH Transcription Factor , Contributes to Leukemogenesis in Concert with LMO 1
OLIG2 (originally designated BHLHB1) encodes a transcription factor that contains the basic helix-loop-helix motif. Although… 
2004
2004
[Suppressive effect of Notch signal activation on apoptosis of multiple myeloma cells].
The proliferation and apoptosis of multiple myeloma (MM) cells were regulated by bone marrow microenvironments in which Notch… 
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