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Dek protein, human

Known as: Protein DEK, DEK Protein, oncoprotein DEK, human 
Protein DEK (375 aa, ~43 kDa) is encoded by the human DEK gene. This protein plays a role in transcriptional regulation via chromatin modification.
National Institutes of Health

Related topics

Related topics

16 relations
Cell NucleusChromatinChromatin Remodeling FactorDEK gene

Broader (2)

Chromosomal Proteins, Non-HistoneOncogene Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Significance of DEK overexpression for the prognostic evaluation of non-small cell lung carcinoma.
In the present study, we explored the role of DEK expression for the prognostic evaluation of non-small cell lung carcinoma… 
2012
2012
DEK regulates hematopoietic stem engraftment and progenitor cell proliferation.
DEK is a biochemically distinct protein that is generally found in the nucleus, where it is vital to global heterochromatin… 
2011
2011
Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer
BackgroundBladder cancer is a significant healthcare problem in the United States of America with a high recurrence rate. Early… 
2010
2010
The Oncogene DEK Promotes Leukemic Cell Survival and Is Downregulated by both Nutlin-3 and Chlorambucil in B-Chronic Lymphocytic Leukemic Cells
Purpose: To characterize the role of the oncogene DEK in modulating the response to either Nutlin-3, a small-molecule inhibitor… 
2006
2006
Hypophosphorylation of the architectural chromatin protein DEK in death‐receptor‐induced apoptosis revealed by the isotope coded protein label proteomic platform
During apoptosis nuclear morphology changes dramatically due to alterations of chromatin architecture and cleavage of structural… 
2005
2005
Expression and significance of tumor-related genes in HCC.
AIM To investigate the expression and clinical significance of DEK, cyclin D1, insulin-like growth factor II (IGF-II), glypican 3… 
2005
2005
Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes.
DEK is an abundant and ubiquitous chromatin protein that has only recently attracted attention. DEK preferentially binds to… 
2000
2000
Autoantibodies to DEK oncoprotein in systemic lupus erythematosus (SLE)
Autoantibodies against the transcriptional DEK protein have been considered characteristic of the pauciarticular onset subtype of… 
1998
1998
Autoantibodies to DEK oncoprotein in a patient with systemic lupus erythematosus and sarcoidosis.
A patient was identified with an unusual autoimmune syndrome consisting of systemic lupus erythematosus and sarcoidosis. Her… 
1991
1991
Dihydroergocryptine in the treatment of Parkinson's disease: a six months' double-blind clinical trial.
The short-term efficacy of dihydro-alpha-ergocryptine (DEK), a hydrogenate ergot derivative with dopamine (DA) agonist properties… 
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