Definitive endoderm

Known as: Embryonic endoderm, Intraembryonic endoderm, Primitive endoderm 
Germ layer facing yolk sac cavity.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Understanding the molecular mechanisms controlling early cell fate decisions in mammals is a major objective toward the… (More)
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Highly Cited
2007
Highly Cited
2007
Human ESCs (hESCs) respond to signals that determine their pluripotency, proliferation, survival, and differentiation status. In… (More)
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Highly Cited
2006
Highly Cited
2006
When differentiated in the presence of activin A in serum-free conditions, mouse embryonic stem cells efficiently generate an… (More)
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Highly Cited
2006
Highly Cited
2006
It has been thought that early inner cell mass (ICM) is a homogeneous population and that cell position in the ICM leads to the… (More)
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Highly Cited
2005
Highly Cited
2005
The potential of human embryonic stem (hES) cells to differentiate into cell types of a variety of organs has generated much… (More)
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Highly Cited
2005
Highly Cited
2005
Preparation of specific lineages at high purities from embryonic stem (ES) cells requires both selective culture conditions and… (More)
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Highly Cited
2005
Highly Cited
2005
Bipotent mesendoderm that can give rise to both endoderm and mesoderm is an established entity from C. elegans to zebrafish… (More)
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Highly Cited
2004
Highly Cited
2004
The cellular and molecular events regulating the induction and tissue-specific differentiation of endoderm are central to our… (More)
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Highly Cited
2002
Highly Cited
2002
In the mouse, the definitive endoderm is derived from the epiblast during gastrulation, and, at the early organogenesis stage… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND After implantation, the basic body plan of the mammalian embryo is established during gastrulation when the epithelial… (More)
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