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Debio 1347

Known as: Debiopharm 1347, FGFR Inhibitor Debio 1347, debio 1347-101 
An orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

CH5183284
NCIt Antineoplastic Agent TerminologyReceptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
Antiretroviral therapy (ART) suppresses HIV replication, but does not cure the infection because replication-competent virus… 
2019
2019
AB065. P-36. Debio 1347 in patients with cholangiocarcinoma harboring an FGFR gene alteration: preliminary results
Background Cholangiocarcinoma (CCA), an aggressive epithelial neoplasm of biliary tract, presents limited treatment options and… 
2018
2018
Safety and efficacy of the selective FGFR inhibitor debio 1347 in phase I study patients with FGFR genomically activated advanced biliary tract cancer (BTC).
447Background: BTC are aggressive tumors with limited treatment options and poor overall survival. Aberrant FGFR signaling has… 
2018
2018
Epidemiology of tuberculosis in Spain. Results obtained by the National Epidemiological Surveillance Network in 2015.
2017
2017
Debio 1347, an oral FGFR inhibitor: Results from a first-in-human, phase I dose-escalation study in patients with FGFR genomically activated advanced solid tumors.
2500Background: Oncogenic alterations in fibroblast growth factor receptors (FGFR) are seen across multiple solid tumor… 
2015
2015
Preliminary clinical pharmacokinetics and pharmacodynamics of Debio 1347 (CH5183284), a novel FGFR inhibitor.
2540 Background: Deregulated fibroblast growth factor receptor (FGFR) signaling is associated with tumorigenesis. Debio 1347 is… 
2011
2011
Oclusión intencional de la arteria subclavia izquierda durante el tratamiento endovascular de la aorta torácica descendente
Resumen es: Introduccion La seguridad y la eficacia del tratamiento endovascular de la aorta toracica descendente dependen de… 
2009
2009
Fenologia de Algumas Espécies do Gênero Cyclocephala (Coleoptera, Scarabaeidae) do Leste e Centro-Oeste do Paraná, Brasil
Sao analisados resultados de capturas de seis especies do genero Cyclocephala (Coleoptera, Scarabaeidae) fototacticos feitas com… 
2008
2008
Tratamiento laparoscópico de la litiasis de la vía biliar principal asociada a litiasis vesicular
Review
1994
Review
1994
Intraspecific structure of the northern right whale dolphin (Lissodelphis borealis): The power of an analysis of molecular variation for differentiating genetic stocks
The northern right whale dolphin (Lissodelphis borealis) has experienced very high levels of fishery-induced mortality in… 
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