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Death Domain

Known as: Death Domains 
The death domain is a protein region, approximately 80 amino acids long, that is required for transmission of the cytotoxic signal of apoptosis and… 
National Institutes of Health

Related topics

Related topics

19 relations
ANK2 protein, humanCASP8 and FADD-Like Apoptosis Regulator ProteinCFLAR protein, humanDAPK1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
TNF receptor superfamily‐induced cell death: redox‐dependent execution
Tumor necrosis factor (TNF) superfamily is a group of cytokines with important functions in immunity, inflammation… 
Review
2004
Review
2004
TIR domain-containing adaptors define the specificity of TLR signaling.
Review
2003
Review
2003
TRAIL-induced signalling and apoptosis.
Highly Cited
2002
Highly Cited
2002
The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1*
The PYRIN and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large… 
Highly Cited
2001
Highly Cited
2001
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.
Highly Cited
2000
Highly Cited
2000
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation.
Highly Cited
1998
Highly Cited
1998
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling
Highly Cited
1997
Highly Cited
1997
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
Highly Cited
1997
Highly Cited
1997
NMR structure of the death domain of the p75 neurotrophin receptor
The intracellular domain of the p75 neurotrophin receptor (p75ICD) lacks catalytic activity but contains a motif similar to death… 
Highly Cited
1996
Highly Cited
1996
CAR1, a TNFR–Related Protein, Is a Cellular Receptor for Cytopathic Avian Leukosis–Sarcoma Viruses and Mediates Apoptosis
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