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Death Domain

Known as: Death Domains 
The death domain is a protein region, approximately 80 amino acids long, that is required for transmission of the cytotoxic signal of apoptosis and… 
National Institutes of Health

Related topics

Related topics

19 relations
ANK2 protein, humanCASP8 and FADD-Like Apoptosis Regulator ProteinCFLAR protein, humanDAPK1 protein, human

Papers overview

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2010
2010
Molecular pathways mediating differential responses to lipopolysaccharide between human and baboon arterial endothelial cells
1. Vascular inflammation plays a critical role in atherogenesis. Previously, we showed that baboon arterial endothelial cells… 
2005
2005
Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis.
2005
2005
FGF signal regulates gastrulation cell movements and morphology through its target NRH.
2004
2004
FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma.
Highly Cited
2000
Highly Cited
2000
Localization of the Death Domain of Tissue Inhibitor of Metalloproteinase-3 to the N Terminus
The tissue inhibitors of metalloproteinases (TIMPs) are a family of four secreted inhibitors of matrix metalloproteinases (MMPs… 
2000
2000
Schizosaccharomyces pombe Rad9 contains a BH3‐like region and interacts with the anti‐apoptotic protein Bcl‐2
Highly Cited
1999
Highly Cited
1999
Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway.
Immunoregulation of lymphocytes and macrophages in the peripheral immune system is achieved in part by activation-induced cell… 
1999
1999
Apoptosis induced by the nuclear death domain protein p84N5 is inhibited by association with Rb protein.
Rb protein inhibits both cell cycle progression and apoptosis. Interaction of specific cellular proteins, including E2F1, with Rb… 
Highly Cited
1998
Highly Cited
1998
Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.
CENP-C, one of the few known intrinsic proteins of the human centromere, is thought to play structural as well as regulatory… 
1998
1998
Characterization of mouse ubiquitin‐like SMT3A and SMT3B cNDAS and gene/pseudogenes
Mouse SMT3A and SMT3B cDNAs encoding ubiquitin‐like proteins of 110 and 95 amino acids, respectively, were isolated and sequenced… 
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