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Daptomycin

Known as: N-Decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon1-lactone, N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine-epsilon1-lactone, Daptomycin [Chemical/Ingredient] 
A semi-synthetic cyclic lipopeptide antibiotic isolated form the bacterium Streptomyces roseosporus with broad-spectrum antibiotic activity against… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (1)

Anti-Bacterial Agents
Bacterial InfectionsDaptomycin 500 MG InjectionDaptomycin:Susc:Pt:Isolate:OrdQnDaptomycin:Susc:Pt:Isolate:OrdQn:Agar diffusion

Narrower (3)

CubicinLY-146032taromycin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Impact of sarA on Daptomycin Susceptibility of Staphylococcus aureus Biofilms In Vivo
ABSTRACT We used a murine model of catheter-associated biofilm formation to determine whether the mutation of the staphylococcal… 
Highly Cited
2007
Highly Cited
2007
LEADER surveillance program results for 2006: an activity and spectrum analysis of linezolid using clinical isolates from the United States (50 medical centers).
Highly Cited
2006
Highly Cited
2006
Spectrum and potency of dalbavancin tested against 3322 Gram-positive cocci isolated in the United States Surveillance Program (2004).
Highly Cited
2004
Highly Cited
2004
Stability, interaction, size, and microenvironmental properties of mixed micelles of decanoyl-N-methylglucamide and sodium dodecyl sulfate.
The mixed micellization between the nonionic surfactant decanoyl-N-methylglucamide (MEGA-10) and the common sodium dodecyl… 
Highly Cited
1991
Highly Cited
1991
Inhibition of membrane potential-dependent amino acid transport by daptomycin
Daptomycin inhibits the formation of UDP-N-acetylmuramyl-pentapeptide in Bacillus megaterium by inhibiting active transport of… 
Highly Cited
1989
Highly Cited
1989
Comparative evaluation of daptomycin (LY146032) and vancomycin in the treatment of experimental methicillin-resistant Staphylococcus aureus osteomyelitis in rabbits
A rabbit model for methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis was used to compare treatment with daptomycin… 
Highly Cited
1986
Highly Cited
1986
Acyl-CoA: glycine N-acyltransferase: in vitro studies on the glycine conjugation of straight- and branched-chained acyl-CoA esters in human liver.
Highly Cited
1986
Highly Cited
1986
Characterization of calf liver glucosidase I and its inhibition by basic sugar analogs.
Highly Cited
1979
Highly Cited
1979
Tumor promoters induce membrane changes detected by fluorescence polarization.
1964
1964
THE STEREOCHEMISTRY OF THE GLUTAMATE MUTASE REACTION *
Abstract 4-Deuterioglutamic acid was prepared by incubation in D2O of ammonium mesaconate with an extract of Clostridium… 
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