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Dapper Homolog 2

Known as: DACT2, Dapper Antagonist of Catenin 2 
Dapper homolog 2 (774 aa, ~83 kDa) is encoded by the human DACT2 gene. This protein is involved in the inhibition of signal transduction.
National Institutes of Health

Papers overview

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2016
2016
Esophageal cancer is one of the most common malignancies worldwide. DACT2 is frequently methylated in human lung, hepatic… Expand
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2016
2016
Delamination of neural crest (NC) cells is a bona fide physiological model of epithelial-to-mesenchymal transition (EMT), a… Expand
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2016
2016
ObjectivesAberrations in Wnt and Shh signaling pathways are related to the pathogenesis of head and neck carcinomas, and their… Expand
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2015
2015
Pilomyxoid astrocytomas (PMAs) manifest a more aggressive clinical course than pilocytic astrocytomas (PAs). Development of… Expand
Review
2014
Review
2014
  • D. Stewart
  • Journal of the National Cancer Institute
  • 2014
  • Corpus ID: 14298118
Wnt/β-catenin alterations are prominent in human malignancies. In non-small cell lung cancer (NSCLC), β-catenin and APC mutations… Expand
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2014
2014
Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is a key regulator of Wnt signaling pathway. The purpose of this… Expand
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2014
2014
Thyroid cancer is the most common endocrine malignant disease and the incidence is increasing. DACT2 was found frequently… Expand
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Highly Cited
2013
Highly Cited
2013
Dapper, Dishevelled‐associated antagonist of β‐catenin (DACT), is involved in Xenopus embryonic development. Human DACT2 is… Expand
Highly Cited
2008
Highly Cited
2008
Systemic sclerosis (SSc) is a complex human disorder characterized by progressive skin fibrosis. To better understand the… Expand
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Review
2005
Review
2005
  • B. Brott, S. Sokol
  • Differentiation; research in biological diversity
  • 2005
  • Corpus ID: 10540055
The Frodo/dapper (Frd) proteins are recently discovered signaling adaptors, which functionally and physically interact with Wnt… Expand