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DVL1 protein, human

Known as: dishevelled 1 protein, human, Dishevelled-1, dishevelled segment polarity protein 1, human 
Segment polarity protein dishevelled homolog DVL-1 (695 aa, ~75 kDa) is encoded by the human DVL1 gene. This protein plays a role in signal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The ciliopathies are a group of heterogeneous diseases with considerable variations in phenotype for allelic conditions such as… Expand
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Highly Cited
2011
Highly Cited
2011
The balance between excitatory and inhibitory synapses is crucial for normal brain function. Wnt proteins stimulate synapse… Expand
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Highly Cited
2008
Highly Cited
2008
Axon guidance and target-derived signals control axonal behavior by regulating the cytoskeleton through poorly defined mechanisms… Expand
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Highly Cited
2008
Highly Cited
2008
In Drosophila, activation of Jun N-terminal Kinase (JNK) mediated by Frizzled and Dishevelled leads to signaling linked to planar… Expand
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Highly Cited
2008
Highly Cited
2008
Wnt proteins regulate the formation of central synapses by stimulating synaptic assembly, but their role at the vertebrate… Expand
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Highly Cited
2006
Highly Cited
2006
Proper dialogue between presynaptic neurons and their targets is essential for correct synaptic assembly and function. At central… Expand
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Highly Cited
2004
Highly Cited
2004
Approximately 20% of familial amyotrophic lateral sclerosis (FALS) arises from germ-line mutations in the superoxide dismutase-1… Expand
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Highly Cited
2004
Highly Cited
2004
Previously we have cloned the human Frizzled 1 (HFz1) and shown that it transmits the Wnt-3a-induced canonical pathway. We also… Expand
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Highly Cited
2003
Highly Cited
2003
Members of the Wnt family of signaling molecules are important in cell specification and epithelial-mesenchymal interactions, and… Expand
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Highly Cited
2001
Highly Cited
2001
One aspect of the function of the β-arrestins is to serve as scaffold or adapter molecules coupling G-protein coupled receptors… Expand
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