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DV 7751a

Known as: 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(8-amino-6-azaspiro(3.4)oct-6-yl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S-(R*,R*))-, DV-7751a 
National Institutes of Health

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DV 7751

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Fluoroquinolones

Papers overview

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2012
2012
The New 4-Quinolones DU-6859a and DV-7751a Show Enhanced Activity against Streptococcus pneumoniae
1997
1997
Toxicological evaluation and disposition of DV-7751a, a new quinolone antimicrobial agent, administered orally to dogs and monkeys.
We examined the toxic potentials and disposition of DV-7751a administered repeatedly to immature beagle dogs and mature… 
1996
1996
One-month oral toxicity study of the new quinolone antibacterial agent (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)-9-fluoro-2,3-dihydro-3- methyl-7-oxo-7H-pyrido [1,2,3-de] [1,4] benzoxazine-6…
One-month oral toxicity of (S)-10-[(S)-(8-amino-6-azaspiro[3,4] octan-6-yl)]-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3… 
1996
1996
LD50 value, phototoxicity and convulsion induction test of the new quinolone antibacterial agent (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3…
(S)-10-[(S)-(8-Amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6… 
1995
1995
Bactericidal activity of the new 4-quinolones DU-6859a and DV-7751a.
The bactericidal activity of two new 4-quinolones, DU-6859a and DV-7751a, was investigated against strains of Escherichia coli… 
1995
1995
In vitro evaluation of DV-7751a, a new fluoroquinolone with an enhanced spectrum of activity against gram-positive aerobic organisms and anaerobes
DV-7751a is an investigational fluoroquinolone with improved spectrum and potency against gram-positive bacteria. We studied the… 
1995
1995
Activity of two novel fluoroquinolones (DU-6859a and DV-7751a) tested against glycopeptide-resistant enterococcal isolates.
1995
1995
Determination of a new fluoroquinolone antimicrobial agent, (S)-10-[(S)-(8-amino-6-azaspiro d3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6- carboxylic…
1995
1995
Pharmacokinetics and tolerance of a new fluoroquinolone antimicrobial drug after single oral doses in healthy volunteers.
1. The pharmacokinetics and tolerance of DV-7751a were investigated in healthy male Caucasian volunteers after single oral doses… 
1993
1993
Antimicrobial activity of DV-7751a, a new fluoroquinolone
We compared the in vitro antibacterial activity of DV-7751a against gram-positive and -negative bacteria with those of quinolones… 
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