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DUX4 gene

Known as: DOUBLE HOMEOBOX PROTEIN 4, DUX4, Double Homeobox 4 Gene 
This gene plays a role in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

9 relations
CIC-DUX SarcomaCIC-DUX4 Fusion Protein ExpressionCell Differentiation processDouble Homeobox Protein 4

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DUX4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Homeotic DUX 4 Genes that Control Human Embryonic Development at the Two-Cell Stage Are Surrounded by Regions Contacting with rDNA Gene Clusters
Many human genes that control human embryonic development and differentiation of human cells form chromosomal contact with rRNA… 
2016
2016
Antisense strategies targeting DUX4 and DUX4c for the treatment of Facioscapulohumeral muscular dystrophy.
2016
2016
Title : Molecular Genotyping of Transposable Elements Insertions in a Population of Uniform Mu Events
There has been rising interest in cytochrome P450 (CYP) proteins due to their implication in tumor progression. CYP3A4 expression… 
2016
2016
DUX4 Rearrangement and ERG Deregulation Characterize a B-ALL Subtype.
ERG deregulation by deletion or expression of a dominant-negative transcript drives a subset of B-ALL. 
2016
2016
The translocation of DUX4 and DUX4c during myoblast differentiation allows their association with nucleo-cytoplasmic proteins associated with mRNP granules.
their association with nucleo-cytoplasmic proteins associated with mRNP granules. Eugénie Ansseau, Jocelyn O. Eidahl, Céline… 
2015
2015
Antisense strategies against DUX4 as a therapeutic approach for FSHD
Facioscapulohumeral muscular dystrophy (FSHD) is a rare hereditary disease linked to a chromatin opening on the D4Z4 repeat array… 
2014
2014
Silencing DUX4 Expression in FSHD Cells by CRISPR
2012
2012
"Chemical inhibitors of DUX4, therapeutic approach for FSHD"
Rising evidence, which is in agreement with our preliminary data, suggests that D4Z4 including DUX4 is a key FSHD effector factor… 
2011
2011
A family history of DUX4 : Phylogenetic analysis of DUXA, B, C and Duxbl reveals the ancestral DUX gene
2008
2008
DUX4 in Cells and Mice
By targeting each FSHD candidate gene to a doxycycline-inducible locus in murine C2 myoblasts, we have shown that DUX4 is… 
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