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DUX4 gene

Known as: DOUBLE HOMEOBOX PROTEIN 4, DUX4, Double Homeobox 4 Gene 
This gene plays a role in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

9 relations
CIC-DUX SarcomaCIC-DUX4 Fusion Protein ExpressionCell Differentiation processDouble Homeobox Protein 4

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DUX4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Important Recently Characterized Non-Ewing Small Round Cell Tumors.
2019
2019
Muscle xenografts reproduce key molecular features of facioscapulohumeral muscular dystrophy
2017
2017
A distal auxiliary element facilitates cleavage and polyadenylation of Dux4 mRNA in the pathogenic haplotype of FSHD
The degenerative muscle disorder facioscapulohumeral dystrophy (FSHD) is thought to be caused by the inappropriate expression of… 
2017
2017
p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
ABSTRACT Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant myopathy caused by mutations that disrupt… 
Review
2016
Review
2016
Integrating clinical and genetic observations in facioscapulohumeral muscular dystrophy.
PURPOSE OF REVIEW This review gives an overview of the currently known key clinical and (epi)genetic aspects of… 
2016
2016
Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis
We performed transcriptome profiling of human immortalized myoblasts (MB) transiently expressing double homeobox transcription… 
2013
2013
Expression of the human FSHD-linked DUX4 gene induces neurogenesis during differentiation of murine embryonic stem cells.
Misexpression of the double homeodomain protein DUX4 in muscle is believed to cause facioscapulohumeral muscular dystrophy (FSHD… 
2011
2011
YY1 associates with the macrosatellite DXZ4 on the inactive X chromosome and binds with CTCF to a hypomethylated form in some male carcinomas
DXZ4 is an X-linked macrosatellite composed of 12–100 tandemly arranged 3-kb repeat units. In females, it adopts opposite… 
2005
2005
Intracellular trafficking and dynamics of double homeodomain proteins.
Double homeodomain (DUX) proteins are encoded by a family of 3.3-kilobase repeated elements dispersed in the human genome. One of… 
2003
2003
Increasing D4Z4 repeat copy number compromises C2C12 myoblast differentiation
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