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Double Homeobox Protein 4
Known as:
DUX4
, Double Homeobox Protein 10
, Double Homeobox Protein 4/10
Double homeobox protein 4 (424 aa, ~45 kDa) is encoded by the human DUX4 gene. This protein plays a role in the regulation of transcription.
National Institutes of Health
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Related topics
Related topics
6 relations
Cell Nucleus
DUX4 gene
Genes, Regulator
Homeodomain Proteins
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Papers overview
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2016
2016
Title : Molecular Genotyping of Transposable Elements Insertions in a Population of Uniform Mu Events
C. Campbell
,
J. Gottesman
,
Evelyn Juliussen
,
Anthony Acholonu
2016
Corpus ID: 39038560
There has been rising interest in cytochrome P450 (CYP) proteins due to their implication in tumor progression. CYP3A4 expression…
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2015
2015
UPF 1 DUX NMD in Facioscapulohumeral Muscular Dystrophy
2015
Corpus ID: 55235067
Next generation sequencing has revolutionized the field of human genetics, and discovery of disease causing mutations continues…
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2012
2012
Inheritance of Two Benign Genetic Variants Causes a Muscular Dystrophy
Matthew E. Arnegard
2012
Corpus ID: 90463799
One of the most common forms of muscular dystrophy, fascioscapulohumeral dystrophy (FSHD), is clinically characterized by the…
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2012
2012
"Small molecule screen to identify inhibitors of DUX4-mediated toxicity, therapeutic approach for FSHD"
D. Bosnakovski
2012
Corpus ID: 51053475
Aim 1. To narrow our focus to the most promising direct DUX4 inhibitors. From the current 82 selected compounds which rescue…
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2011
2011
A possible approach for treating FSHD with RNAi therapeutics
2011
Corpus ID: 34949143
Treatment of dominantly inherited muscle disorders remains a difficult task considering the need to eliminate the pathogenic gene…
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