DUSP6 gene

Known as: DUSP6, MKP3, PYST1 
This gene plays a role in MAP kinase dephosphorylation.
National Institutes of Health

Papers overview

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2013
2013
Congenital hypogonadotropic hypogonadism (CHH) and its anosmia-associated form (Kallmann syndrome [KS]) are genetically… (More)
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2012
Highly Cited
2012
The ability of the human immune system to respond to vaccination declines with age. We identified an age-associated defect in T… (More)
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2011
2011
DUSP6/MKP-3 is a cytoplasmic dual-specificity phosphatase specific for the MAP kinases ERK1/2. Previous data have shown that the… (More)
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2010
Highly Cited
2010
Mitogen-activated protein kinase (MAPK) pathway signaling plays an important role in the majority of non-small-cell lung cancers… (More)
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2009
2009
Our preliminary studies revealed that oncogenic KRAS (KRAS/V12) dramatically suppressed the growth of immortalized airway… (More)
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Highly Cited
2008
Highly Cited
2008
DUSP6 (dual-specificity phosphatase 6), also known as MKP-3 [MAPK (mitogen-activated protein kinase) phosphatase-3] specifically… (More)
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Highly Cited
2008
Highly Cited
2008
The strength and duration of mitogen-activated protein kinase signaling is regulated through phosphorylation and… (More)
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2007
Highly Cited
2007
Mitogen-activated protein kinase (MAPK) pathways are major mediators of extracellular signals that are transduced to the nucleus… (More)
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Highly Cited
2005
Highly Cited
2005
AbstractOur previous study indicated that DUSP6/MKP-3/PYST1 could act as a tumor suppressor in human pancreatic cancer. DUSP6 was… (More)
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Highly Cited
2005
Highly Cited
2005
DUSP6/MKP-3 is identified as a candidate tumor suppressor gene for pancreatic cancer. The aim of this study was to elucidate the… (More)
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