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DUSP16 gene

Known as: DUSP16, MKP-7, DUAL-SPECIFICITY PHOSPHATASE 16 
 
National Institutes of Health

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DUSP15 gene

Papers overview

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2018
2018
MicroRNA-27a-3p inhibits cell viability and migration through down-regulating DUSP16 in hepatocellular carcinoma.
MicroRNA (miRNA or miR) has been shown to play an important role in the initiation and development in many different cancers… Expand
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2015
2015
MAPK phosphatase 7 regulates T cell differentiation via inhibiting ERK-mediated IL-2 expression.
Members of the MAPK phosphatase (MKP) protein family play critical roles in immune responses through differential regulation of… Expand
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2013
2013
Gene Trap Mice Reveal an Essential Function of Dual Specificity Phosphatase Dusp16/MKP-7 in Perinatal Survival and Regulation of Toll-like Receptor (TLR)-induced Cytokine Production*
Background: Dual specificity phosphatases (DUSPs) have emerged as important regulators of MAPK signaling and responses, including… Expand
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2011
2011
A distinct interaction mode revealed by the crystal structure of the kinase p38α with the MAPK binding domain of the phosphatase MKP5.
The mitogen-activated protein kinase (MAPK) cascades play a pivotal role in a myriad of cellular functions… Expand
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2011
2011
Functional involvement of dual specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, in the regulation of T helper cell differentiation.
Naïve CD4(+) T helper (Th) cells differentiate into distinct subsets of effector cells (Th1, Th2, Th17, and induced regulatory T… Expand
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Highly Cited
2010
Highly Cited
2010
Cumulus cell gene expression is associated with oocyte developmental quality and influenced by patient and treatment characteristics.
BACKGROUND Gene expression of cumulus cells (CC) could predict oocyte developmental quality. Knowledge of the genes involved in… Expand
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2010
2010
DUSP16 is an epigenetically regulated determinant of JNK signalling in Burkitt's lymphoma
Background:The mitogen-activated protein kinase (MAPK) phosphatases or dual specificity phosphatases (DUSPs) are a family of… Expand
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2005
2005
Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2.
JNK scaffold proteins bind JNK and upstream kinases to activate subsets of JNK and localize activated JNK to specific subcellular… Expand
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2003
2003
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK.
The c-Jun N-terminal kinase (JNK) group of mitogen-activated protein kinases (MAPKs) are activated by pleiotropic signals… Expand
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2003
2003
Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446.
We previously showed that MKP-7 suppresses MAPK activation in COS-7 cells in the order of selectivity, JNK >> p38 > ERK, but… Expand
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