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DUSP16 gene

Known as: DUSP16, MKP-7, DUAL-SPECIFICITY PHOSPHATASE 16 
National Institutes of Health

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DUSP15 gene

Papers overview

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Review
2019
Review
2019
Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability
Mitogen-activated protein kinases (MAPKs) are key regulators of signal transduction and cell responses. Abnormalities in MAPKs… 
2018
2018
MicroRNA‐27a‐3p inhibits cell viability and migration through down‐regulating DUSP16 in hepatocellular carcinoma
MicroRNA (miRNA or miR) has been shown to play an important role in the initiation and development in many different cancers… 
2016
2016
Axonal Degeneration Is Regulated by a Transcriptional Program that Coordinates Expression of Pro- and Anti-degenerative Factors
2014
2014
miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7
Here we show that transgenic expression of miR-17 extends lifespan and inhibits cellular senescence. We propose that miR-17 acts… 
2011
2011
A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38α with the MAPK Binding Domain of the Phosphatase MKP5
Identification of the mechanism through which the kinase p38α interacts with the phosphatase that inactivates it could lead to… 
Highly Cited
2010
Highly Cited
2010
Cumulus cell gene expression is associated with oocyte developmental quality and influenced by patient and treatment characteristics.
BACKGROUND Gene expression of cumulus cells (CC) could predict oocyte developmental quality. Knowledge of the genes involved in… 
Highly Cited
2005
Highly Cited
2005
Dynamic Interaction between the Dual Specificity Phosphatase MKP7 and the JNK3 Scaffold Protein β-Arrestin 2*
JNK scaffold proteins bind JNK and upstream kinases to activate subsets of JNK and localize activated JNK to specific subcellular… 
Highly Cited
2005
Highly Cited
2005
Phosphorylation of Ser-446 Determines Stability of MKP-7*
MAPK cascades can be negatively regulated by members of the MAPK phosphatase (MKP) family. However, how MKP activity is regulated… 
Highly Cited
2003
Highly Cited
2003
The JNK-interacting Protein-1 Scaffold Protein Targets MAPK Phosphatase-7 to Dephosphorylate JNK*
The c-Jun N-terminal kinase (JNK) group of mitogen-activated protein kinases (MAPKs) are activated by pleiotropic signals… 
Highly Cited
2003
Highly Cited
2003
Activation of ERK Induces Phosphorylation of MAPK Phosphatase-7, a JNK Specific Phosphatase, at Ser-446*
We previously showed that MKP-7 suppresses MAPK activation in COS-7 cells in the order of selectivity, JNK ≫ p38 > ERK, but… 
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