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DU-PAN-2

Known as: Sialyl Le(c), Sialylated Lewis (c) Antigen, Sialyl Lewis (c) 
A sialylated carbohydrate antigen that is found in serum at elevated levels in pancreatic cancer and other neoplastic diseases. DU-PAN-2 is related… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Unusual reactivity in organoaluminium and NHC chemistry: deprotonation of AlMe3 by an NHC moiety involving the formation of a sterically bulky NHC-AlMe3 Lewis adduct.
A sterically congested NHC-AlMe(3) Lewis adduct (NHC = 1,3-di-tert-butylimidazol-2-ylidene) was found to either isomerize to an… 
2010
2010
An Ultrasound Contrast Agent Targeted to P-Selectin Detects Activated Platelets at Supra-Arterial Shear Flow Conditions
Objectives:To evaluate targeting of a microbubble contrast agent to platelets under high shear flow using the natural selectin… 
Highly Cited
2008
Highly Cited
2008
Expression of CD175 (Tn), CD175s (sialosyl‐Tn) and CD176 (Thomsen‐Friedenreich antigen) on malignant human hematopoietic cells
The expression of the histo‐blood group carbohydrate structures T‐nouvelle (Tn, CD175), sialylated Tn (CD175s) and the Thomsen… 
Highly Cited
2004
Highly Cited
2004
Molecular basis of the dynamic strength of the sialyl Lewis X--selectin interaction.
The selectins are Ca(2+)-dependent cell adhesion molecules that facilitate the initial attachment of leukocytes to the vascular… 
Highly Cited
1994
Highly Cited
1994
Structure--activity relationships of sialyl Lewis x-containing oligosaccharides. 1. Effect of modifications of the fucose moiety.
Leukocyte adhesion to the vasculature is mediated by E-, P-, and L-selectins. The natural ligands for E- and P-selectins have not… 
Highly Cited
1992
Highly Cited
1992
P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.
1990
1990
Structure determination of five sialylated trisaccharides with core types 1, 3 or 5 isolated from bovine submaxillary mucin.
In this study we have investigated the structures of five sialylated trisaccharides released from bovine submaxillary mucin by… 
Highly Cited
1988
Highly Cited
1988
Significance of 2‐3 and 2‐6 sialylation of Lewis A antigen in pancreas cancer
Distributions of sialylated derivatives of Lewis a (Lea) antigen in cancer tissue of the human pancreas and in the sera of… 
Highly Cited
1987
Highly Cited
1987
The GDP-fucose:N-acetylglucosaminide 3-alpha-L-fucosyltransferases of LEC11 and LEC12 Chinese hamster ovary mutants exhibit novel specificities for glycolipid substrates.
Highly Cited
1986
Highly Cited
1986
Biosynthesis of the sialyl-Lex determinant carried by type 2 chain glycosphingolipids (IV3NeuAcIII3FucnLc4, VI3NeuAcV3FucnLc6, and VI3NeuAcIII3V3Fuc2nLc6) in human lung carcinoma PC9 cells.
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