DPYD gene

Known as: DPYD, DPD, DIHYDROPYRIMIDINE DEHYDROGENASE 
This gene is involved in pyrimidine catabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
024619902018

Papers overview

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2011
2011
We describe the identification and clinical presentation of four individuals from three unrelated families with hemizygous… (More)
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2009
2009
AIMS The importance of polymorphisms in the dihydropyrimidine dehydrogenase gene (DPYD) for the prediction of severe toxicity in… (More)
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2008
2008
BACKGROUND Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience… (More)
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2007
2007
AbstractDihydropyrimidine dehydrogenase (DPD) is an inactivating and rate-limiting enzyme for 5-fluorouracil (5-FU), and its… (More)
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2006
2006
Dihydropyrimidine dehydrogenase (DPD), the initial and rate-limiting enzyme in the 5-fluorouracil (5-FU) catabolic pathway, has… (More)
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2005
2005
PURPOSE Complete or partial loss of dihydropyrimidine dehydrogenase (DPD) function has been described in cancer patients with… (More)
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2003
2003
Dihydropyrimidine dehydrogenase (DPD) enzyme deficiency is a pharmacogenetic syndrome with possible fatal outcome following 5… (More)
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2002
2002
5-fluorouracil pharmacokinetics, dihydropyrimidine dehydrogenase-activity and DNA sequence analysis were compared between a… (More)
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2000
2000
Dihydropyrimidine dehydrogenase (DPD) is the rate-limiting enzyme in the degradation of pyrimidine bases and pyrimidine-based… (More)
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1998
1998
Dihydropyrimidine dehydrogenase (DPD) catabolizes endogenous pyrimidines and pyrimidine-based antimetabolite drugs. A deficiency… (More)
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