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Dihydropyrimidine Dehydrogenase Deficiency
Known as:
Pyrimidinemia, Familial
, Hereditary Thymine-Uraciluria
, Thymine-Uracilurias, Hereditary
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An autosomal recessive disorder affecting DIHYDROPYRIMIDINE DEHYDROGENASE and causing familial pyrimidinemia. It is characterized by thymine…
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National Institutes of Health
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Related topics
Related topics
26 relations
Autistic Disorder
Autosomal recessive inheritance
Cerebral atrophy
Congenital ocular coloboma (disorder)
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Synthesis of alkoxyphthalimide derivatized oxoimidazolidinyl oxazolo/thiazolo dihydropyrimidine and oxoimidazolidinyl tetrahydropyrimidine via common Schiff base intermediate and evaluation of their…
Monika Kumawat
,
Bhawana Kherodiya
,
Prakash Prajapat
,
G. L. Talesara
2015
Corpus ID: 86041033
Synthesis of N-(2-(4-substituted phenyl)-3-(2-(1,3-dioxoisoindolin-2-yloxy)ethyl)-5-oxoimidazolidin-1-yl)-3-(2-(1…
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2010
2010
Distance-Patterns of Vertices in a Graph
K. A. Germina
2010
Corpus ID: 52236964
Given a connected simple (p, q)-graph G = (V,E) and ∅ = M ⊆ V, we initiate a study of the set-valued function f : V → 2M…
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2007
2007
u-헬스케어 지원 분산 프레임워크에서 접근 제어 모델을 이용한 동적 보안 서비스
정창원
,
김동호
,
김명희
,
주수종
2007
Corpus ID: 140073533
본 논문은 분산 보안 정책을 지정하기 위해 객체그룹을 사용하는 u-헬스케어 컴퓨팅 환경에서 응용 서비스를 위해 동적보안 서비스를 지원하는데 설계된 보안 객체에 대해 기술한다. 특히 u…
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2005
2005
BiDil raises questions about race as a marker
M. Branca
Nature reviews. Drug discovery
2005
Corpus ID: 7810757
Approval of 'race-based' drug is stimulating efforts to detect and predict true subgroups for drug response
Review
2004
Review
2004
Lethal Toxicity After 5-Fluorouracil Chemotherapy and Its Possible Relationship to Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Review
R. Díaz
,
A. Segura
,
J. Aparicio
,
V. Calderero
,
Á. Guerrero
,
L. Pellín
Journal of chemotherapy
2004
Corpus ID: 36065224
Abstract 5- fluorouracil (5-FU) is a chemotherapeutic agent widely used in the treatment of solid malignancies, especially in…
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2003
2003
Theoretical Study of Alkali Metals Interactions with Thymine Tautomers: Comparison and Analysis #
M. Monajjemi
,
R. Ghiasi
,
+6 authors
F. Asaddian
2003
Corpus ID: 55175965
Motivation. The interaction of alkali metal with thymine is an interesting target of studies in connection with bioinorganic…
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Review
1996
Review
1996
Individualizing therapy with 5-fluorouracil related to dihydropyrimidine dehydrogenase: theory and limits.
G. Milano
,
M. Etienne
Therapeutic Drug Monitoring
1996
Corpus ID: 2927073
5-Fluorouracil (FU) is metabolized by dihydropyrimidine dehydrogenase (DPD). Patients with suspected or proven DPD deficiency…
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1986
1986
The effect of macrophage development on the release of reactive oxygen intermediates and lipid oxidation products, and their ability to induce oxidative DNA damage in mammalian cells.
J. Lewis
,
T. Hamilton
,
D. Adams
Carcinogenesis
1986
Corpus ID: 19535756
Inflammation and the release of potentially damaging substances, such as reactive oxygen intermediates (ROI) and lipid oxidation…
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1981
1981
Alternative metabolic fates of thymine nucleotides in human cells.
M. Taheri
,
R. Wickremasinghe
,
A. Hoffbrand
Biochemical Journal
1981
Corpus ID: 10909639
Three types of experiments have been used to study the metabolism of thymine nucleotides by human cells. (1) Cells were labelled…
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1962
1962
Effect of γ-rays on Thymine in De-aerated Aqueous Solutions
B. Ekert
Nature
1962
Corpus ID: 4171774
IT is well known that X-irradiation of the pyrimidine bases in aqueous solutions in the presence of oxygen causes peroxidation at…
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