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DOCK8 gene

Known as: FLJ00026, FLJ00152, DOCK8 
This gene may play a role in guanine nucleotide exchange
National Institutes of Health

Related topics

Related topics

2 relations
DOCK7 geneSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Multiplexed detection of DOCK8, PGM3 and STAT3 proteins for the diagnosis of Hyper-Immunoglobulin E syndrome using gold nanoparticles-based immunosensor array platform.
2017
2017
DOCK8 Drives Src-Dependent NK Cell Effector Function
Mutations in the dedicator of cytokinesis 8 (DOCK8) gene cause an autosomal recessive form of hyper-IgE syndrome, characterized… 
2017
2017
DOCK8 and STAT3 dependent inhibition of IgE isotype switching by TLR9 ligation in human B cells.
2014
2014
Expansion of CCR4+ activated T cells is associated with memory B cell reduction in DOCK8-deficient patients.
2014
2014
Acute eosinophilic pneumonia occurring in a dedicator of cytokinesis 8 (DOCK8) deficient patient
Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive type of combined immunodeficiency with elevated IgE. In… 
2013
2013
Aberrant humoral immune reactivity in DOCK8 deficiency with follicular hyperplasia and nodal plasmacytosis.
Review
2011
Review
2011
Hyperimmunoglobulin E syndromes in pediatrics
Purpose of review The hyper-IgE syndromes (HIES) are primary immunodeficiencies characterized by eczema, sinopulmonary infections… 
2011
2011
Clinical, immunological and genetic features in Taiwanese patients with the phenotype of hyper-immunoglobulin E recurrent infection syndromes (HIES).
Review
2010
Review
2010
Visualizing a role for the actin cytoskeleton in the regulation of B‐cell activation
Summary:  Appropriate activation of B cells is required for mounting protective humoral immune responses. B‐cell activation is… 
Review
2010
Review
2010
Combined Immunodeficiency Associated with DOCK8 Mutations and Related Immunodeficiencies
Studying rare inherited immune disorders in patients has led to improved understanding of how the human immune system is… 
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