DNM2 gene

Known as: DI-CMTB, CMTDI1, CMT2M 
This gene plays a role in both GTP hydrolysis and microtubule organization.
National Institutes of Health

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CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE B (disorder)Cell Cycle ProgressionCytoskeletal ModelingCytoskeletal Proteins
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DNM2 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed… (More)
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Highly Cited
2010
Highly Cited
2010
Endocytosis of murine norovirus 1 into murine macrophages is dependent on dynamin II and cholesterol.
Although noroviruses cause the vast majority of nonbacterial gastroenteritis in humans, little is known about their life cycle… (More)
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Highly Cited
2009
Highly Cited
2009
Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins.
Cell migration requires the controlled disassembly of focal adhesions, but the underlying mechanisms remain poorly understood… (More)
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Highly Cited
2007
Highly Cited
2007
CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
The preservation of vascular endothelial cell (EC) barrier integrity is critical to normal vessel homeostasis, with barrier… (More)
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Highly Cited
2007
Highly Cited
2007
Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells.
It is well-known that dynamin 2 (Dyn2) participates in clathrin- and caveolae-mediated endocytosis; however, the role of Dyn2 in… (More)
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Highly Cited
2004
Highly Cited
2004
Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.
Binding of echovirus 1 (EV1, a nonenveloped RNA virus) to the alpha2beta1 integrin on the cell surface is followed by endocytic… (More)
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Highly Cited
2004
Highly Cited
2004
Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL.
We have previously identified the cystic fibrosis transmembrane regulator (CFTR)-interacting protein CAL and demonstrated that… (More)
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Highly Cited
2003
Highly Cited
2003
Dynamin participates in focal extracellular matrix degradation by invasive cells.
The degradation of extracellular matrix (ECM) by matrix metalloproteases is crucial in physiological and pathological cell… (More)
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Highly Cited
2002
Highly Cited
2002
Dynamin at actin tails.
Dynamin, the product of the shibire gene of Drosophila, is a GTPase critically required for endocytosis. Some studies have… (More)
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Highly Cited
1991
Highly Cited
1991
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
We have isolated a cDNA encoding a third type of protein-tyrosine-phosphatase. We screened human megakaryoblastic cell line (MEG… (More)
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