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DNK 333
Known as:
DNK-333
, DNK333
, N-((R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl)carbamoyl)allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Aza Compounds
Benzamides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Raznolikost mitohondrijske DNK divlje mačke u Hrvatskoj – preliminarni rezultati
M. Sindičić
,
M. Jagić
,
N. Šprem
,
V. Slijepcevic
,
R. Popović
,
D. Konjević
2016
Corpus ID: 188852308
2014
2014
Response to Keszthelyi and Masclee
M. Wouters
,
Dafne Balemans
,
Guy E. Boeckxstaens
American Journal of Gastroenterology
2014
Corpus ID: 205100429
To the Editor: We thank Keszthelyi and Masclee (1) for their interest in our study and are pleased to note that they agree with…
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2014
2014
Capsaicin Stimulation In Irritable Bowel Syndrome: Toward Understanding Visceral Perception and Pain Symptom Generation
D. Keszthelyi
,
A. Masclee
American Journal of Gastroenterology
2014
Corpus ID: 36769254
Capsaicin Stimulation In Irritable Bowel Syndrome: Toward Understanding Visceral Perception and Pain Symptom Generation
2011
2011
Randomised clinical trial: the clinical effects of a novel neurokinin receptor antagonist, DNK333, in women with diarrhoea‐predominant irritable bowel syndrome
S. Zakko
,
G. Barton
,
E. Weber
,
C. Dunger-Baldauf
,
A. Rühl
Alimentary Pharmacology and Therapeutics
2011
Corpus ID: 13069774
Background Neurokinin receptors may play an important role in the visceral hypersensitivity and exaggerated motor/secretory…
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Review
2007
Review
2007
Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig.
Christine Lewis
,
C. Ambrose
,
+7 authors
Chris Poll
Pulmonary Pharmacology & Therapeutics
2007
Corpus ID: 24310024
Review
2006
Review
2006
When Knowledge is Not Enough: Hiv/Aids Information and Risky Behavior in Botswana
Taryn Dinkelman
,
J. Levinsohn
,
R. Majelantle
2006
Corpus ID: 143012858
The spread of the HIV/AIDS epidemic is still fueled by ignorance in many parts of the world. Filling in knowledge gaps…
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Highly Cited
2004
Highly Cited
2004
Dual tachykinin NK1/NK2 antagonist DNK333 inhibits neurokinin A‐induced bronchoconstriction in asthma patients
Guy Joos
,
Walter Vincken
,
+5 authors
R. Pauwels
European Respiratory Journal
2004
Corpus ID: 8020379
Inhalation of neurokinin A (NKA) causes bronchoconstriction in patients with asthma. In vitro both tachykinin NK1 and NK2…
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2004
2004
The airways pharmacology of DNK333, a potent, selective, non‐peptide dual NK1/NK2 receptor antagonist
C. Lewis
,
A. El-Hashim
,
+5 authors
J. Fozard
2004
Corpus ID: 73291607
The airways' pharmacology of DNK333 ((1R,3R,2E)‐N‐[3,4‐dichlorobenzyl)]‐4‐[(hexahydro‐2‐oxo‐1H‐azepin‐3‐yl)amino]‐N‐methyl‐3,5bis…
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2003
2003
Stereoselective preparation of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide, a potent and orally active dual neurokinin NK(1)/NK…
M. Gerspacher
,
C. Lewis
,
+4 authors
J. Fozard
Journal of Medicinal Chemistry
2003
Corpus ID: 23538232
In a program aimed at the development of neurokinin antagonists, N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3-(2-oxoazepan-3-yl…
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2001
2001
Dual neurokinin NK(1)/NK(2) antagonists: N-[(R,R)-(E)-1-arylmethyl-3-(2-oxo-azepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamides and 3-[N'-3,5-bis(trifluoromethyl)benzoyl-N…
M. Gerspacher
,
L. La Vecchia
,
+9 authors
H. Ball
Bioorganic & Medicinal Chemistry Letters
2001
Corpus ID: 33334035
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