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DNA topoisomerase III alpha

Known as: TOP3alpha, TOPO IIIalpha, topoisomerase IIIalpha 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

DNA topoisomerase III
TOP3A gene

Narrower (1)

TOP3A protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIIα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells
In Alternative Lengthening of Telomeres (ALT) cell lines, specific nuclear bodies called APBs (ALT-associated PML bodies… Expand
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Highly Cited
2008
Highly Cited
2008
Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load
The biogenesis of endoplasmic reticulum (ER) exit sites (ERES) involves the formation of phosphatidylinositol‐4 phosphate (PI4… Expand
2007
2007
Holliday junction processing activity of the BLM-Topo IIIalpha-BLAP75 complex.
BLM, the protein mutated in Bloom's syndrome, possesses a helicase activity that can dissociate DNA structures, including the… Expand
Highly Cited
2006
Highly Cited
2006
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates.
BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability… Expand
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Highly Cited
2006
Highly Cited
2006
Sgs1 Regulates Gene Conversion Tract Lengths and Crossovers Independently of Its Helicase Activity
ABSTRACT RecQ helicases maintain genome stability and suppress tumors in higher eukaryotes through roles in replication and DNA… Expand
Highly Cited
2006
Highly Cited
2006
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells.
DNA glycosylases/AP lyases initiate repair of oxidized bases in the genomes of all organisms by excising these lesions and then… Expand
Highly Cited
2006
Highly Cited
2006
Bloom Helicase and DNA Topoisomerase IIIα Are Involved in the Dissolution of Sister Chromatids
ABSTRACT Bloom's syndrome (BS) is an autosomal disorder characterized by predisposition to a wide variety of cancers. The gene… Expand
Highly Cited
2005
Highly Cited
2005
Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector.
Crigler-Najjar syndrome is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by a… Expand
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2005
2005
Drosophila melanogaster Topoisomerase IIIα Preferentially Relaxes a Positively or Negatively Supercoiled Bubble Substrate and Is Essential during Development*
Eukaryotic type IA topoisomerases are important for the normal function of the cell, and in some cases essential for the organism… Expand
Highly Cited
2000
Highly Cited
2000
The Bloom's Syndrome Gene Product Interacts with Topoisomerase III*
  • Leonard Wu, S. Davies, +5 authors I. Hickson
  • The Journal of Biological Chemistry
  • 2000
    • Corpus ID: 26410285
Bloom's syndrome is a rare genetic disorder associated with loss of genomic integrity and a large increase in the incidence of… Expand
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