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DNA topoisomerase III alpha

Known as: TOP3alpha, TOPO IIIalpha, topoisomerase IIIalpha 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In Alternative Lengthening of Telomeres (ALT) cell lines, specific nuclear bodies called APBs (ALT-associated PML bodies… 
Highly Cited
2008
Highly Cited
2008
The biogenesis of endoplasmic reticulum (ER) exit sites (ERES) involves the formation of phosphatidylinositol‐4 phosphate (PI4… 
Highly Cited
2007
Highly Cited
2007
BLM, the protein mutated in Bloom's syndrome, possesses a helicase activity that can dissociate DNA structures, including the… 
Highly Cited
2006
Highly Cited
2006
BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT RecQ helicases maintain genome stability and suppress tumors in higher eukaryotes through roles in replication and DNA… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Bloom's syndrome (BS) is an autosomal disorder characterized by predisposition to a wide variety of cancers. The gene… 
Highly Cited
2005
Highly Cited
2005
Crigler-Najjar syndrome is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by a… 
Highly Cited
2000
Highly Cited
2000
Bloom's syndrome is a rare genetic disorder associated with loss of genomic integrity and a large increase in the incidence of… 
1999
1999
Human topoisomerase IIIalpha (hTopo IIIalpha), the recently identified first member of the topoisomerase IA subfamily in humans…