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DNA topoisomerase III alpha

Known as: TOP3alpha, TOPO IIIalpha, topoisomerase IIIalpha 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In Alternative Lengthening of Telomeres (ALT) cell lines, specific nuclear bodies called APBs (ALT-associated PML bodies… Expand
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Highly Cited
2008
Highly Cited
2008
The biogenesis of endoplasmic reticulum (ER) exit sites (ERES) involves the formation of phosphatidylinositol‐4 phosphate (PI4… Expand
2007
2007
BLM, the protein mutated in Bloom's syndrome, possesses a helicase activity that can dissociate DNA structures, including the… Expand
Highly Cited
2006
Highly Cited
2006
BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT RecQ helicases maintain genome stability and suppress tumors in higher eukaryotes through roles in replication and DNA… Expand
Highly Cited
2006
Highly Cited
2006
DNA glycosylases/AP lyases initiate repair of oxidized bases in the genomes of all organisms by excising these lesions and then… Expand
Highly Cited
2006
Highly Cited
2006
ABSTRACT Bloom's syndrome (BS) is an autosomal disorder characterized by predisposition to a wide variety of cancers. The gene… Expand
Highly Cited
2005
Highly Cited
2005
Crigler-Najjar syndrome is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia caused by a… Expand
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2005
2005
Eukaryotic type IA topoisomerases are important for the normal function of the cell, and in some cases essential for the organism… Expand
Highly Cited
2000
Highly Cited
2000
  • Leonard Wu, S. Davies, +5 authors I. Hickson
  • The Journal of Biological Chemistry
  • 2000
  • Corpus ID: 26410285
Bloom's syndrome is a rare genetic disorder associated with loss of genomic integrity and a large increase in the incidence of… Expand
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