TOP3A protein, human

Known as: TOPO III Alpha, DNA Topoisomerase III Alpha, EC 5.99.1.2

DNA topoisomerase 3-alpha (1001 aa, ~112 kDa) is encoded by the human TOP3A gene. This protein is involved in the relaxation of supercoiled DNA.

National Institutes of Health

Papers overview

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2014

Purpose: Human DNA topoisomerase III alpha (hTOP3α) is involved in DNA repair surveillance and cell-cycle checkpoints possibly…