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DNA polymerase processivity factor activity

Known as: processivity clamp, sliding clamp 
An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along… Expand
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
The proliferating cell nuclear antigen (PCNA) is an essential protein for DNA replication and damage repair. How its function is… Expand
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Highly Cited
2005
Highly Cited
2005
Posttranslational modification of proliferating cell nuclear antigen (PCNA), an essential processivity clamp for DNA polymerases… Expand
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Review
2005
Review
2005
DNA replicases are multicomponent machines that have evolved clever strategies to perform their function. Although the structure… Expand
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Highly Cited
2004
Highly Cited
2004
Sliding clamps are ring-shaped proteins that encircle DNA and confer high processivity on DNA polymerases. Here we report the… Expand
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Highly Cited
2004
Highly Cited
2004
Five MutS homologs (MSH), which form three heterodimeric protein complexes, have been identified in eukaryotes. While the human… Expand
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Review
2003
Review
2003
Proliferating cell nuclear antigen (PCNA) was originally characterised as a DNA sliding clamp for replicative DNA polymerases and… Expand
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Highly Cited
2002
Highly Cited
2002
The RAD6 pathway is central to post-replicative DNA repair in eukaryotic cells; however, the machinery and its regulation remain… Expand
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Highly Cited
1999
Highly Cited
1999
We have solved the crystal structures of the bacteriophage RB69 sliding clamp, its complex with a peptide essential for DNA… Expand
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Highly Cited
1999
Highly Cited
1999
The damage-inducible UmuD' and UmuC proteins are required for most SOS mutagenesis in Escherichia coli. Our recent assay to… Expand
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Highly Cited
1991
Highly Cited
1991
DNA polymerase III holoenzyme (holoenzyme), the multiprotein replicase of Escherichia coli, is essentially unlimited in… Expand
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