DNA polymerase processivity factor activity

Known as: processivity clamp, sliding clamp 
An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
010203019812017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Break-induced replication (BIR) is an efficient homologous recombination (HR) pathway employed to repair a DNA double-strand… (More)
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Highly Cited
2005
Highly Cited
2005
This report demonstrates that the beta sliding clamp of E. coli binds two different DNA polymerases at the same time. One is the… (More)
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Highly Cited
2005
Highly Cited
2005
The DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) is central to both DNA replication and repair… (More)
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Highly Cited
2004
Highly Cited
2004
Sliding clamps are ring-shaped proteins that encircle DNA and confer high processivity on DNA polymerases. Here we report the… (More)
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2003
2003
Chromosomal DNA polymerases are tethered to DNA by a circular sliding clamp for high processivity. However, lagging strand… (More)
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Highly Cited
2002
Highly Cited
2002
The RAD6 pathway is central to post-replicative DNA repair in eukaryotic cells; however, the machinery and its regulation remain… (More)
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Highly Cited
2001
Highly Cited
2001
The dimeric ring-shaped sliding clamp of E. coli DNA polymerase III (beta subunit, homolog of eukaryotic PCNA) is loaded onto DNA… (More)
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Highly Cited
1999
Highly Cited
1999
We have solved the crystal structures of the bacteriophage RB69 sliding clamp, its complex with a peptide essential for DNA… (More)
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Highly Cited
1999
Highly Cited
1999
The damage-inducible UmuD' and UmuC proteins are required for most SOS mutagenesis in Escherichia coli. Our recent assay to… (More)
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Highly Cited
1999
Highly Cited
1999
This study reports a primase-to-polymerase switch in E. coli that closely links primase action with extension by DNA polymerase… (More)
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