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DNA polymerase processivity factor activity

Known as: processivity clamp, sliding clamp 
An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

DNA metabolic process

Narrower (1)

PCNA complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Separation of replication and transcription domains in nucleoli.
Highly Cited
2011
Highly Cited
2011
Artificial molecular clamp: a novel device for synthetic polymerases.
Highly Cited
2004
Highly Cited
2004
The clamp-loading complex for processive DNA replication
DNA polymerase requires two processing factors, sliding clamps and clamp loaders, to direct rapid and accurate duplication of… 
2004
2004
The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase.
Transcription of bacteriophage T4 late genes requires concomitant DNA replication. T4 late promoters, which consist of a single 8… 
Highly Cited
2002
Highly Cited
2002
Elucidation of an Archaeal Replication Protein Network to Generate Enhanced PCR Enzymes*
Thermostable DNA polymerases are an important tool in molecular biology. To exploit the archaeal repertoire of proteins involved… 
Highly Cited
2002
Highly Cited
2002
A bipartite bacteriophage T4 SOC and HOC randomized peptide display library: detection and analysis of phage T4 terminase (gp17) and late sigma factor (gp55) interaction.
Highly Cited
2001
Highly Cited
2001
MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp.
In the yeast Saccharomyces cerevisiae, mismatch repair (MMR) is initiated by the binding of heterodimeric MutS homolog (MSH… 
Highly Cited
1999
Highly Cited
1999
The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp.
The accessory subunit of the heterodimeric mtDNA polymerase (polgamma) from Drosophila embryos is required to maintain the… 
Highly Cited
1998
Highly Cited
1998
Replication Factor C Disengages from Proliferating Cell Nuclear Antigen (PCNA) upon Sliding Clamp Formation, and PCNA Itself Tethers DNA Polymerase δ to DNA*
Replication factor C (RF-C) and proliferating cell nuclear antigen (PCNA) assemble a complex, called sliding clamp, onto DNA. The… 
1998
1998
Triplex-directed self-assembly of an artificial sliding clamp on duplex DNA.
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