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DNA Structure

The structure of a DNA molecule, consisting of its primary nucleotide sequence as well as its secondary and tertiary arrangement in space.
National Institutes of Health

Papers overview

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2010
2010
Cytosines, but Not Purines, Determine Recombination Activating Gene (RAG)-induced Breaks on Heteroduplex DNA Structures
The sequence specificity of the recombination activating gene (RAG) complex during V(D)J recombination has been well studied… 
2000
2000
Role of the N- and C- Terminal Dimer Interfaces of 434 Repressor in Recognizing Sequence-Dependent DNA Structure
Abstract The binding of proteins to specific DNA sequences plays a central role in the regulation of gene expression. Crucial to… 
Review
1996
Review
1996
Sequence-dependent DNA structure.
The three-dimensional structure of DNA depends subtly on its sequence, and this property is used by the proteins that regulate… 
1996
1996
Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria.
DNA repair alkyltransferases protect organisms against the cytotoxic, mutagenic, and carcinogenic effects of alkylating agents by… 
1994
1994
Periodicity of DNA bend sites in human epsilon-globin gene region. Possibility of sequence-directed nucleosome phasing.
Analysis by the circular permutation assay of the human epsilon-globin gene region revealed that the DNA bend sites were located… 
Highly Cited
1991
Highly Cited
1991
Strong sequence-dependent polymorphism in adduct-induced DNA structure: analysis of single N-2-acetylaminofluorene residues bound within the NarI mutation hot spot.
We have used a set of chemical probes to characterize and to compare the structural deformation of double-stranded oligomers… 
Highly Cited
1990
Highly Cited
1990
Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle
Mitochondrial DNA (mt DNA) in cells of vertebrate organisms can assume an unusual triplex DNA structure known as the displacement… 
1987
1987
Nature of recombination involved in excision and rearrangement of human repetitive DNA.
Review
1978
Review
1978
Conformational flexibility in DNA structure as revealed by structural studies of drug intercalation and its broader implications in understanding the organization of DNA in chromatin.
This paper reviews evidence for conformational flexibility in DNA structure (i.e., the kink) as revealed by structural studies of… 
1969
1969
Studies on conformational changes in the DNA structure induced by protonation: Reversible and irreversible acid titrations and sedimentation measurements
Reversible and irreversible conformational changes in the acid‐induced denaturation of DNA were studied by spectrophotometric… 
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