DNA Ligation

The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. [ISBN:0815316194]
National Institutes of Health

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2009
2009
Ataxia oculomotor apraxia 1 (AOA1) results from mutations in aprataxin, a component of DNA strand break repair that removes AMP… (More)
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Highly Cited
2007
Highly Cited
2007
The double-strand DNA break repair pathway, non-homologous DNA end joining (NHEJ), is distinctive for the flexibility of its… (More)
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2006
Highly Cited
2006
Ataxia oculomotor apraxia-1 (AOA1) is a neurological disorder caused by mutations in the gene (APTX) encoding aprataxin… (More)
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Highly Cited
2004
Highly Cited
2004
Nonhomologous end joining (NHEJ) is the major DNA double-strand break (DSB) repair pathway in mammalian cells. A critical step in… (More)
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Highly Cited
2004
Highly Cited
2004
The extraordinary radiation resistance of Deinococcus radiodurans results from the efficient capacity of the bacterium to repair… (More)
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2002
Highly Cited
2002
The advent of in vitro DNA amplification has enabled rapid acquisition of genomic information. We present here an analogous… (More)
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2002
2002
Association studies using common sequence variants or single nucleotide polymorphisms (SNPs) may provide a powerful approach to… (More)
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2001
2001
Ligase-mediated gene detection has proven valuable for detection and precise distinction of DNA sequence variants. We have… (More)
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2000
2000
Agrobacterium tumefaciens, a gram-negative soil bacterium, transfers DNA to many plant species. In the plant cell, the… (More)
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1997
Highly Cited
1997
Arsenic has been shown to inhibit methyl methane-sulphonate (MMS)-induced DNA repair but the exact mechanism remains… (More)
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