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DNA Fragmentation

Known as: Fragmentation, DNA 
Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which… 
National Institutes of Health

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Related topics

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DFFB geneDFFB protein, humanDFFB wt AlleleDNA Degradation, Necrotic

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apoptotic DNA fragmentation

Papers overview

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2007
2007
Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL‐2‐independent apoptosis in human prostatic adenocarcinoma cells
Elevated BCL‐2 is one mechanism of therapeutic resistance in prostate cancer (PC), and new approaches are needed to overcome such… 
Highly Cited
2004
Highly Cited
2004
Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables.
Highly Cited
2001
Highly Cited
2001
The Absence of Oligonucleosomal DNA Fragmentation during Apoptosis of IMR-5 Neuroblastoma Cells
Caspase-activated DNase is responsible for the oligonucleosomal DNA degradation during apoptosis. DNA degradation is thought to… 
Highly Cited
1999
Highly Cited
1999
Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells.
Highly Cited
1998
Highly Cited
1998
Glutathione-independent mechanism of apoptosis inhibition by curcumin in rat thymocytes.
Highly Cited
1997
Highly Cited
1997
Transfection of p53-knockout mouse fibroblasts with wild-type p53 increases the thermosensitivity and stimulates apoptosis induced by heat stress.
Highly Cited
1995
Highly Cited
1995
Endonuclease activity and induction of DNA fragmentation in human myelogenous leukemic cell lines.
When four human myelogenous leukemic cell lines (HL-60, ML-1, U-937, THP-1) were exposed to either ascorbic acid, hydrogen… 
Highly Cited
1995
Highly Cited
1995
High molecular weight DNA fragmentation: a critical event in nucleoside analogue-induced apoptosis in leukemia cells.
Cleavage of DNA into internucleosomal fragments is one of the characteristics of apoptosis. However, searches for in vivo… 
Highly Cited
1994
Highly Cited
1994
Ca2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons
Highly Cited
1994
Highly Cited
1994
Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms.
Incubation of human thymocytes with an optimum concentration of adenosine and its receptor site agonist, 2-chloroadenosine… 
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