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DN 9693

Known as: DN-9693 
National Institutes of Health

Papers overview

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2006
2006
Novel angiogenic inhibitor DN-9693 that inhibits post-transcriptional induction of connective tissue growth factor (CTGF/CCN2) by vascular endothelial growth factor in human endothelial cells
Connective tissue growth factor (CTGF/CCN2) is a potent angiogenic factor. In this report, we describe for the first time that… 
1995
1995
Effects of a New Inotropic Drug (DN‐9693) on Ca2+ Transients and Contraction in Ferret Ventricular Muscles
We investigated the mechanisms of the effects of a newly synthesized cyclic AMP phosphodiesterase inhibitor (PDEI: l,5-dihydro-7… 
1991
1991
Interactions between prostaglandin E2 and inhibitors of platelet aggregation which act through cyclic AMP.
1991
1991
Effect of a cyclic adenosine monophosphate phosphodiesterase inhibitor, DN-9693, on myocardial reperfusion injury.
1989
1989
Effects of DN-9693, a synthesized phosphodiesterase inhibitor, on pancreatic exocrine secretion in dogs.
The effects of DN-9693, a synthesized phosphodiesterase inhibitor, on the secretion of pancreatic juice were investigated in… 
1987
1987
Comparison of vasodilator effects of DN-9693, a selective inhibitor of cyclic AMP phosphodiesterase, and isobutylmethylxanthine, a non-selective one, in dogs.
The present experiments were performed in anesthetized dogs in order to determine if DN-9693, a new antiplatelet agent known to… 
1987
1987
Determination of 7-piperidino-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-one (DN-9693) in human plasma and urine by high-performance liquid chromatography with electrochemical detection…
A procedure for the determination of a newly developed antiadhesive agent, 7-piperidino-1,2,3,5-tetrahydroimidazo[2,1-b… 
1986
1986
Phosphorylation of phosphoinositides in human platelets.
1986
1986
Effects of DN-9693, a new metastasis inhibitor, on murine hematogenous metastasis.
1,5-Dihydro-7-(1-piperidinyl)-imidazo[2,1-b]quinazolin-2(3H)-one dihydrochloride hydrate (DN-9693), a new c-AMP… 
1985
1985
Cyclic guanidines. 17. Novel (N-substituted amino)imidazo[2,1-b]quinazolin-2 ones: water-soluble platelet aggregation inhibitors.
A series of novel 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-one derivatives substituted with a secondary amino group has been… 
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