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DL-threo-beta-benzyloxyaspartate

Known as: DL-TBOA, TBOA 
National Institutes of Health

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Broader (1)

benzyloxyaspartate

Papers overview

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Highly Cited
2009
Highly Cited
2009
Experimental glutamatergic excitotoxicity in rabbit retinal ganglion cells: block by memantine.
PURPOSE Excessive activity of NMDA-type (N-methyl-d-aspartate) glutamatergic channels has been implicated as a mechanism for… 
Highly Cited
2007
Highly Cited
2007
Glutamate transporter GLAST/EAAT1 directs cell surface expression of FXYD2/γ subunit of Na, K-ATPase in human fetal astrocytes
2007
2007
The beta‐lactam antibiotic, ceftriaxone, attenuates morphine‐evoked hyperthermia in rats
Beta‐lactam antibiotics are the first practical pharmaceuticals capable of increasing the expression and activity of the… 
2007
2007
Two conformational changes are associated with glutamate translocation by the glutamate transporter EAAC1.
Glutamate is transported across membranes by means of a carrier mechanism that is thought to require conformational changes of… 
2007
2007
Inhibition of Glutamate Transporters Results in a “Suppression‐Burst” Pattern and Partial Seizures in the Newborn Rat
Summary:  Purpose: To determine the electrophysiological pattern and propose a clinical relevance of a deficient glutamate… 
2005
2005
Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta
Excitatory synaptic inputs from the subthalamic nucleus (STN) have been proposed to underlie burst firing of substantia nigra… 
2004
2004
Isolation of glutamate transport-coupled charge flux and estimation of glutamate uptake at the climbing fiber-Purkinje cell synapse.
Excitatory amino acid transporters (EAATs) located on neurons and glia are responsible for limiting extracellular glutamate… 
2003
2003
Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using dl-threo-β-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and…
2002
2002
Evaluation of Drugs Acting at Glutamate Transporters in Organotypic Hippocampal Cultures: New Evidence on Substrates and Blockers in Excitotoxicity
Removal of L-glutamate (Glu) from the synapse is critical to maintain normal transmission and to prevent excitotoxicity, and is… 
Highly Cited
2000
Highly Cited
2000
Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers.
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