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DIRAS3 wt Allele

Known as: Distinct Subgroup of the Ras Family, Member 3 Gene, DIRAS Family, GTP-Binding RAS-Like 3 wt Allele, NOEY2 
Human DIRAS3 wild-type allele is located in the vicinity of 1p31 and is approximately 6 kb in length. This allele, which encodes GTP-binding protein… 
National Institutes of Health

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7 relations
1p31ARHI protein, humanHomo sapiensSignal Transduction

Broader (1)

DIRAS3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Expression levels of ARHI and Beclin1 in thyroid cancer and their relationship with clinical pathology and prognosis
Expression levels of autophagy-related genes ARHI and Beclin1 in thyroid cancer and their relationship with clinical pathology… 
2017
2017
Genetic causes and risk factors associated with phenotypes occurring in mitochondrial disorders
Finding the genetic causes leading to phenotypes of mitochondrial diseases is challenging because of heterogeneity of the… 
2014
2014
ARHI Overexpression Induces Epithelial Ovarian Cancer Cell Apoptosis and Excessive Autophagy
Objective ARHI is a maternally imprinted tumor suppressor gene that is responsible for initiating programmed cell death and… 
2014
2014
Over-expression of ARHI decreases tumor growth, migration, and invasion in human glioma
This study was conducted to evaluate the role of tumor suppressor gene ras homologue member I (ARHI) in human glioma tumors. We… 
2014
2014
EZH2-Induced H3K27me3 is Associated with Epigenetic Repression of the ARHI Tumor-Suppressor Gene in Ovarian Cancer
Epithelial ovarian cancer (EOC) is the second leading cause of death from gynecological malignancies worldwide. Enhancer of zeste… 
2013
2013
Inhibitory effect of ARHI on pancreatic cancer cells and NF-κB activity.
The aim of this study was to investigate the effect of aplasia ras homolog member I (ARHI) on proliferation, apoptosis and the… 
2012
2012
The expression of ARHI in pT2a and pT2b stage gastric cancer and its clinical significance.
ARHI is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected… 
2009
2009
ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins.
ARHI (aplasia Ras homologue member I; also known as DIRAS3) is an imprinted tumour suppressor gene, the expression of which is… 
Highly Cited
2004
Highly Cited
2004
Expression of the Tumor Suppressor Gene ARHI in Epithelial Ovarian Cancer Is Associated with Increased Expression of p21WAF1/CIP1 and Prolonged Progression-Free Survival
Purpose: ARHI, an imprinted putative tumor suppressor gene, is expressed in normal ovarian epithelial cells, but its expression… 
Highly Cited
2000
Highly Cited
2000
ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers
In our previous work, we had characterized ARHI as an imprinted putative tumor‐suppressor gene in ovarian and breast cancers… 
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