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DIRAS3 wt Allele

Known as: Distinct Subgroup of the Ras Family, Member 3 Gene, DIRAS Family, GTP-Binding RAS-Like 3 wt Allele, NOEY2 
Human DIRAS3 wild-type allele is located in the vicinity of 1p31 and is approximately 6 kb in length. This allele, which encodes GTP-binding protein… 
National Institutes of Health

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Related topics

7 relations
1p31ARHI protein, humanHomo sapiensSignal Transduction

Broader (1)

DIRAS3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
ARHI Overexpression Induces Epithelial Ovarian Cancer Cell Apoptosis and Excessive Autophagy
Objective ARHI is a maternally imprinted tumor suppressor gene that is responsible for initiating programmed cell death and… 
2014
2014
Over-expression of ARHI decreases tumor growth, migration, and invasion in human glioma
This study was conducted to evaluate the role of tumor suppressor gene ras homologue member I (ARHI) in human glioma tumors. We… 
2013
2013
The tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms
ARHI is an imprinted tumor suppressor gene that is downregulated in > 60% of ovarian cancers, associated with decreased… 
2013
2013
Inhibitory effect of ARHI on pancreatic cancer cells and NF-κB activity.
The aim of this study was to investigate the effect of aplasia ras homolog member I (ARHI) on proliferation, apoptosis and the… 
2009
2009
ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins.
ARHI (aplasia Ras homologue member I; also known as DIRAS3) is an imprinted tumour suppressor gene, the expression of which is… 
Highly Cited
2005
Highly Cited
2005
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer
Deoxycytosine methylation within CpG islands of tumor suppressor genes plays a prominent role in the development and progression… 
2005
2005
RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential.
Ras proteins are members of a superfamily of related small GTPases. Some members, such as Ras, are oncogenic. However, other… 
Highly Cited
2004
Highly Cited
2004
Expression of the Tumor Suppressor Gene ARHI in Epithelial Ovarian Cancer Is Associated with Increased Expression of p21WAF1/CIP1 and Prolonged Progression-Free Survival
Purpose: ARHI, an imprinted putative tumor suppressor gene, is expressed in normal ovarian epithelial cells, but its expression… 
2002
2002
ARHI/NOEY2 Inactivation May Be Important in Breast Tumor Pathogenesis
Allelic loss frequently occurs on the short arm of chromosome 1 in human breast carcinoma, suggesting that the ARHI/NOEY2 gene… 
Highly Cited
2000
Highly Cited
2000
ARHI is the center of allelic deletion on chromosome 1p31 in ovarian and breast cancers
In our previous work, we had characterized ARHI as an imprinted putative tumor‐suppressor gene in ovarian and breast cancers… 
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