Skip to search formSkip to main contentSkip to account menu

DES gene

Known as: DES, CMD1I, Desmin Gene 
This gene is involved in the maintenance of muscle cell structure.
National Institutes of Health

Related topics

Related topics

13 relations
Cardiac Muscle ContractionCell MovementCytokinesisCytoskeletal Modeling

Narrower (1)

DES wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations
A genomewide screen of a collection of 4,847 yeast gene deletion mutants was carried out to identify the genes required for… 
Highly Cited
2000
Highly Cited
2000
Desmin Cytoskeleton Linked to Muscle Mitochondrial Distribution and Respiratory Function
Ultrastructural studies have previously suggested potential association of intermediate filaments (IFs) with mitochondria. Thus… 
Highly Cited
1999
Highly Cited
1999
The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function.
Desmin is the muscle-specific member of the intermediate filament family of cytoskeletal proteins, expressed both in striated and… 
Highly Cited
1997
Highly Cited
1997
Null mutation in the desmin gene gives rise to a cardiomyopathy.
A null mutation in the desmin gene has been introduced into the germ line of mice. Such mice develop and reproduce normally… 
Highly Cited
1988
Highly Cited
1988
Phosphorylation of desmin in vitro inhibits formation of intermediate filaments; identification of three kinase A sites in the aminoterminal head domain.
The in vitro phosphorylation of chicken desmin by the catalytic subunit of cAMP‐dependent protein kinase was analysed… 
Highly Cited
1984
Highly Cited
1984
Immunocytochemical Detection of Desmin in Fat‐Storing Cells (Ito Cells)
Desmin is a smooth muscle protein consisting of intermediate filaments. It is also present in other cell types. We obtained… 
Highly Cited
1983
Highly Cited
1983
Monoclonal antibodies to desmin, the muscle‐specific intermediate filament protein.
A set of monoclonal antibodies to desmin has been isolated from a fusion of mouse myeloma cells with spleen cells from mice… 
Highly Cited
1983
Highly Cited
1983
Immunoelectron microscopic studies of desmin (skeletin) localization and intermediate filament organization in chicken skeletal muscle
We studied the localization of desmin (skeletin), the major subunit of muscle-type intermediate filaments, by high resolution… 
Highly Cited
1982
Highly Cited
1982
The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.
The complete amino acid sequence of muscle desmin reported here is the first for an intermediate filament protein. Alignment with… 
Highly Cited
1979
Highly Cited
1979
Coexistence of desmin and the fibroblastic intermediate filament subunit in muscle and nonmuscle cells: identification and comparative peptide analysis.
Extraction of chicken embryo fibroblasts (CEF) or baby hamster kidney (BHK) cells with 1% Triton X-100 and 0.6 M KCl leaves an… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)