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DEC1 gene

Known as: DELETED IN ESOPHAGEAL CANCER 1, CTS9, DEC1 
This gene may play a role in tumor suppression.
National Institutes of Health

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7 relations
BHLHE40 geneCell Proliferation Regulatory ProcessDEC1 proteinHomo sapiens

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DEC1 wt Allele

Papers overview

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2020
2020
DEC1 directly interacts with estrogen receptor (ER) α to suppress proliferation of ER-positive breast cancer cells.
2019
2019
The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling
Here we study the effects of differentiated embryonic chondrocyte gene 1(DEC1) deficiency on midbrain dopaminergic(DA) neurons in… 
2017
2017
Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes
Inflammatory burden is a primary cellular event in many liver diseases, and the overall capacity of drug elimination is decreased… 
2017
2017
Abstract 456: Functional analysis of DEC1 and DEC2 in cancer metabolism
2013
2013
Profiling of Circadian Genes Expressed in the Uterus Endometrial Stromal Cells of Pregnant Rats as Revealed by DNA Microarray Coupled with RNA Interference
The peripheral circadian oscillator plays an essential role in synchronizing local physiology to operate in a circadian manner… 
2011
2011
ΔNp63, a Target of DEC1 and Histone Deacetylase 2, Modulates the Efficacy of Histone Deacetylase Inhibitors in Growth Suppression and Keratinocyte Differentiation*
The p63 gene, a member of the p53 family, is expressed as TA and ΔN isoforms. ΔNp63 is the predominant isoform expressed in cells… 
2009
2009
Liver X receptors (LXRα and LXRβ) are potent regulators for hepatic Dec1 expression
DEC1 (BHLHB2/Stra13/Sharp2)—a basic helix‐loop‐helix transcription factor—is known to be involved in various biological phenomena… 
2002
2002
A decarboxylase encoded at the Cochliobolus heterostrophus translocation-associated Tox1B locus is required for polyketide (T-toxin) biosynthesis and high virulence on T-cytoplasm maize.
Genes at two unlinked loci (Tox1A and Tox1B) are required for production of the polyketide T-toxin by Cochliobolus heterostrophus… 
2002
2002
Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32
2000
2000
Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32
The long arm of chromosome 9 is thought to contain one or more putative tumor suppressor genes that are mutated in squamous cell… 
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