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DEC1 protein

Known as: Candidate Tumor Suppressor CTS9, DEC1, Deleted in Esophageal Cancer 1 
Encoded by human DEC1 Gene, widely expressed 70-amino acid DEC1 Protein is a candidate tumor suppressor protein of unknown function; possibly… 
National Institutes of Health

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BHLHE40 geneCandidate Tumor Suppressor GeneCell Proliferation Regulatory ProcessDEC1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Transcription factor DEC1 is required for maximal experimentally induced periodontal inflammation
BACKGROUND AND OBJECTIVES Disruption of transcriptional regulation is a confounding factor associated with a wide range of human… 
2017
2017
DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells.
Differentiated embryonic chondrocyte (DEC) 1 has been reported to be involved in cell differentiation, hypoxia response, and… 
2017
2017
Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes
Inflammatory burden is a primary cellular event in many liver diseases, and the overall capacity of drug elimination is decreased… 
2012
2012
Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1
Activation of p53 upon DNA damage induces an array of target genes, leading to cell cycle arrest and/or apoptosis. However, the… 
2011
2011
ΔNp63, a Target of DEC1 and Histone Deacetylase 2, Modulates the Efficacy of Histone Deacetylase Inhibitors in Growth Suppression and Keratinocyte Differentiation*
The p63 gene, a member of the p53 family, is expressed as TA and ΔN isoforms. ΔNp63 is the predominant isoform expressed in cells… 
2011
2011
Significant dissociation of expression patterns of the basic helix–loop–helix transcription factors Dec1 and Dec2 in rat kidney
SUMMARY Dec1 and Dec2 are regulators of the mammalian molecular clock that show robust circadian rhythms in the suprachiasmatic… 
2009
2009
Liver X receptors (LXRα and LXRβ) are potent regulators for hepatic Dec1 expression
DEC1 (BHLHB2/Stra13/Sharp2)—a basic helix‐loop‐helix transcription factor—is known to be involved in various biological phenomena… 
Highly Cited
2008
Highly Cited
2008
Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells.
2008
2008
Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage‐independent growth properties and impact on global gene expression in esophageal carcinoma
Previous studies showed that expression of the novel candidate tumor suppressor gene, DEC1 (Deleted in Esophageal Cancer 1), is… 
2006
2006
Hypoxic Treatment Inhibits Insulin-Induced Chondrogenesis of ATDC5 Cells Despite Upregulation of DEC1
Chondrogenesis occurs in vivo in a hypoxic environment, in which the hypoxia inducible factor 1, HIF-1, plays a regulatory role… 
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