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DDX10 gene

Known as: DDX10, HRH-J8, DEAD-box helicase 10 
This gene plays a role in both RNA metabolism and ATP hydrolysis.
National Institutes of Health

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10 relations
ATP HydrolysisDDX10 protein, humanDDX20 geneDNA Repair
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DDX10 wt Allele

Papers overview

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2013
2013
Inv(11)(p15q22)/NUP98-DDX10 fusion and isoforms in a new case of de novo acute myeloid leukemia.
We set up a diagnostic double-color double-fusion fluorescence in situ hybridization (DCDF-FISH) assay to investigate a case of a… Expand
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2010
2010
Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: Role of a conserved helicase motif
NUP98 gene rearrangements occur in acute myeloid leukemia and result in the expression of fusion proteins. One of the most… Expand
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2005
2005
Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia.
The BCR/ABL tyrosine kinase inhibitor imatinib has shown remarkable efficacy in treating patients with chronic myelogenous… Expand
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2004
2004
Anterior pituitary thyrotropes are multifunctional cells.
Anterior pituitary (AP) contains some unorthodox multifunctional cells that store and secrete two different AP hormones… Expand
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Review
2003
Review
2003
Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).
The NUP98 gene at 11p15 is known to be fused to DDX10, HOXA9, HOXA11, HOXA13, HOXD11, HOXD13, LEDGF, NSD1, NSD3, PMX1, RAP1GDS1… Expand
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2000
2000
Fusion of the nucleoporin gene, NUP98, and the putative RNA helicase gene, DDX10, by inversion 11 (p15q22) chromosome translocation in a patient with etoposide-related myelodysplastic syndrome.
We report a 50-year-old man who developed therapy-related myelodysplastic syndrome after treatment with etoposide-including… Expand
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1999
1999
The inv(11)(p15q22) chromosome translocation of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts.
Chromosomal abnormalities involving the 11p15 or 11q22-23 bands have been reported in several types of human neoplasms including… Expand
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Highly Cited
1997
Highly Cited
1997
The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10.
The inv(11)(p15q22) is a recurrent chromosomal abnormality associated with de novo and therapy-related myeloid malignancies. Here… Expand
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1997
1997
The inv ( 11 ) ( p 15 q 22 ) Chromosome Translocation of De Novo and Therapy-Related Myeloid Malignancies Results in Fusion of the Nucleoporin Gene , NUP 98 , With the Putative RNA Helicase Gene
The inv(11)(p15q22) is a recurrent chromosomal abnormality location. Although two reciprocal chimeric products, NUP98DDX10 and… Expand
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1996
1996
A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23.
A human gene encoding a putative RNA helicase, designated DDX10, was identified 400 kb telomeric to the ataxia-telangiectasia… Expand
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