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DCLRE1C gene

Known as: DNA Cross-Link Repair 1C Gene, SNM1C, FLJ11360 
This gene is involved in both DNA repair and V(D)J recombination.
National Institutes of Health

Related topics

Related topics

8 relations
DCLRE1A geneDCLRE1B geneHydrolysisNon-Homologous DNA End-Joining

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DCLRE1C wt Allele

Papers overview

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2020
2020
CD3ε+ Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS
Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes… 
2019
2019
NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV
The recombination-activating genes (RAGs) and the DNA cross-link repair 1C gene (DCLRE1C) encode the enzymes RAG1, RAG2 and… 
2018
2018
Abstract 1537: Anti-CD19 ARTEMIS™ T cells prevent excessive inflammatory cytokine release, including IL-6, in a co-culture model of CRS
We designed the ARTEMISTM T-cell signaling platform to be a safer ACT therapy by relying on endogenous T-cell signaling factors… 
2016
2016
NK CELLS FROM PATIENTS WITH RAG AND ARTEMIS DEFICIENCY HAVE AN IMMATURE PHENOTYPE AND DISPLAY INCREASED DEGRANULATION CAPACITY – IMPLICATIONS FOR HEMATOPOIETIC CELL TRANSPLANTATION
2015
2015
Lymphopoiesis in transgenic mice over-expressing Artemis
Artemis is a factor of the non-homologous end joining pathway involved in DNA double-strand break repair that has a critical role… 
2014
2014
DNA methylation in the placenta and in cancerwith special reference to folate transporting genes
The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical lesions and development of cervical cancer… 
2005
2005
Targeted Disruption of the Artemis Murine Counterpart Results in SCID and Defective V(D)J Recombination That Is Partially Corrected with Bone Marrow Transplantation1
Artemis is a mammalian protein, the absence of which results in SCID in Athabascan-speaking Native Americans (SCIDA). This novel… 
Review
2003
Review
2003
Artemis, a novel guardian of the genome.
B and T lymphocytes recognize foreign antigen through specialized receptors: the immunoglobulins and the T cell receptors… 
Highly Cited
2002
Highly Cited
2002
Cell and chloroplast division requires ARTEMIS
Chloroplasts are endosymbiotic organelles of cyanobacterial origin. It seems reasonable to assume that cell division and… 
1998
1998
Complex-Pulsed Autologous Dendritic Cells Mice Immunized with Antigen-Mouse IgG2a -SCID hu-PBL Human IgG Production by High Titer, Prostate Specific Antigen-Specific
We report here that immunization of human PBMC reconstituted SCID mice ( hu - PBL -SCID mice) with in vitro cultured autologous… 
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