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DC 159a
Known as:
DC-159a
, DC159a
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Antibacterial Activity of DC-159a Against Salmonella Typhimurium.
Kentaro Koide
,
S. Kongsoi
,
Y. Ouchi
,
Tomoyuki Yamaguchi
,
C. Nakajima
,
Yasuhiko Suzuki
Microbial Drug Resistance
2019
Corpus ID: 51711379
Quinolones show excellent antibacterial activity against Salmonella isolates. Recently, however, quinolone resistance has been…
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Review
2017
Review
2017
Tackling Drug-Resistant Tuberculosis: Current Trends and Approaches.
R. Tandon
,
M. Nath
Mini-Reviews in Medical Chemistry
2017
Corpus ID: 23776075
Tuberculosis is very much rampant in our society and accounts for a large number of deaths annually. In spite of consistent…
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2016
2016
DC-159a Shows Inhibitory Activity against DNA Gyrases of Mycobacterium leprae
Tomoyuki Yamaguchi
,
Kazumasa Yokoyama
,
C. Nakajima
,
Yasuhiko Suzuki
PLoS Neglected Tropical Diseases
2016
Corpus ID: 11560002
Background Fluoroquinolones are a class of antibacterial agents used for leprosy treatment. Some new fluoroquinolones have been…
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Review
2015
Review
2015
The anti-tuberculosis agents under development and the challenges ahead.
Deepak Kumar
,
Beena Negi
,
D. Rawat
Future Medicinal Chemistry
2015
Corpus ID: 5688
Tuberculosis (TB) is a serious health problem causing 1.5 million deaths worldwide. After the discovery of first-line anti-TB…
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2011
2011
Activity of the Fluoroquinolone DC-159a in the Initial and Continuation Phases of Treatment of Murine Tuberculosis
Z. Ahmad
,
Austin Minkowski
,
+4 authors
E. Nuermberger
Antimicrobial Agents and Chemotherapy
2011
Corpus ID: 33587165
ABSTRACT DC-159a is a new fluoroquinolone with more potent in vitro activity than available fluoroquinolones against both drug…
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Review
2011
Review
2011
Fluoroquinolones, the cornerstone of treatment of drug-resistant tuberculosis: a pharmacokinetic and pharmacodynamic approach.
A. Pranger
,
J. Alffenaar
,
R. Aarnoutse
Current pharmaceutical design
2011
Corpus ID: 34712223
Fluoroquinolones (FQs) are important drugs to treat drug-resistant tuberculosis. In this review we integrated pharmacokinetic…
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2010
2010
Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats.
Koichi Goto
,
K. Yabe
,
Takami Suzuki
,
T. Jindo
,
A. Sanbuissho
Toxicology
2010
Corpus ID: 66661
2008
2008
Comparative In Vitro Activities of the Investigational Fluoroquinolone DC-159a and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas
K. Waites
,
D. Crabb
,
L. Duffy
Antimicrobial Agents and Chemotherapy
2008
Corpus ID: 44997801
ABSTRACT The in vitro susceptibilities of 151 unique clinical isolates of Mycoplasma pneumoniae, Mycoplasma hominis, Mycoplasma…
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2008
2008
Antimicrobial Activity of DC-159a, a New Fluoroquinolone, against 1,149 Recently Collected Clinical Isolates
Ronald N. Jones
,
T. Fritsche
,
H. Sader
Antimicrobial Agents and Chemotherapy
2008
Corpus ID: 25126709
ABSTRACT The activity of DC-159a, a novel orally administered fluorinated quinolone, was evaluated by reference broth…
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2007
2007
In Vitro Activity of DC-159a, a New Broad-Spectrum Fluoroquinolone, Compared with That of Other Agents against Drug-Susceptible and -Resistant Pneumococci
Catherine L. Clark
,
Kathy Smith
,
+4 authors
P. Appelbaum
Antimicrobial Agents and Chemotherapy
2007
Corpus ID: 24760146
ABSTRACT DC-159a yielded MICs of ≤1 μg/ml against 316 strains of both quinolone-susceptible and -resistant pneumococci…
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