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DACA, acridine

Known as: Acridine Carboxamide, DACA, N-(2-(Dimehtylamino)ethyl)acridine-4-carboxamide 
A tricyclic acridine-based (or carboxamide-based) drug with dual topoisomerase inhibitor and potential antineoplastic activities. Acridine… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Acridines
NCIt Antineoplastic Agent Terminology

Narrower (2)

NSC 601316XR 5000

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Undocumented Students Pursuing Medical Education: The Implications of Deferred Action for Childhood Arrivals (DACA)
There are about 1.8 million young immigrants in the United States who came or were brought to the country without documentation… 
2013
2013
Evaluation of Rhesus Monkey and Guinea Pig Hepatic Cytosol Fractions as Models for Human Aldehyde Oxidase
Aldehyde oxidase (AOX) is a cytosolic enzyme expressed across a wide range of species, including guinea pig and rhesus monkey… 
2004
2004
Experimental solid tumour activity ofN-[2-(dimethylamino)ethyl]-acridine-4-carboxamide
N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide (DACA), a DNA intercalator that exerts its antitumour action through the enzyme… 
Review
2003
Review
2003
Phase II study of XR 5000 (DACA), an inhibitor of topoisomerase I and II, administered as a 120-h infusion in patients with non-small cell lung cancer.
Highly Cited
2002
Highly Cited
2002
Anticancer, antiradical and antioxidative actions of novel Antoksyd S and its major components, baicalin and baicalein.
Here we show for the first time that the novel designed drug, Antoksyd S and its polyphenolic flavones (baicalin and baicalein… 
Highly Cited
1998
Highly Cited
1998
Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: A feasibility study
Purpose: The aim of this study was to investigate the feasibility of evaluating the pharmacokinetics of radiolabeled anti-cancer… 
1998
1998
Distal anterior cerebral artery aneurysms: a clinical series.
Thirty patients with distal anterior cerebral artery (DACA) aneurysms were seen at the Royal Adelaide Hospital in the period 1970… 
1993
1993
Amino acid substitutions at position 47 of human beta 1 beta 1 and beta 2 beta 2 alcohol dehydrogenases affect hydride transfer and coenzyme dissociation rate constants.
1993
1993
Learning and Recognition of 3-D Objects from Brightness Images *
We address the problem of automatically learning object models for recognition and pose estimation. In contrast to the… 
1979
1979
A simple assay for measurement of urinary p-aminobenzoic acid in the oral pancreatic function test.
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