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Cytoplasmic inclusion (cell structure)

Known as: Cytoplasmic Inclusion, inclusion cell, cells inclusions 
A stainable aggregation of protein, lipid or small molecules in the cytoplasm.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (2)

Cellular StructuresInclusion Bodies
CytoplasmLewy BodiesNegri Body

Narrower (3)

Cytoplasmic GranulesLafora bodiesguarnieri bodies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
Highly Cited
2014
Highly Cited
2014
Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
Highly Cited
2014
Highly Cited
2014
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have distinct clinical features but a common pathology… 
Highly Cited
2008
Highly Cited
2008
Neuroinflammation and Oxidation/Nitration of α-Synuclein Linked to Dopaminergic Neurodegeneration
α-Synuclein (SYN) is the major component of Lewy bodies, the neuropathological hallmarks of Parkinson's disease (PD). Missense… 
Highly Cited
2008
Highly Cited
2008
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
TAR DNA-binding protein (TDP-43) has been recently described as a major pathological protein in both frontotemporal dementia with… 
Highly Cited
2004
Highly Cited
2004
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.
Parkinson's disease (PD) is characterized by a progressive loss of midbrain dopamine neurons and the presence of cytoplasmic… 
Highly Cited
2004
Highly Cited
2004
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP 1 1 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Review
1999
Review
1999
Biochemical and genetic analysis of PHA synthases and other proteins required for PHA synthesis.
Highly Cited
1998
Highly Cited
1998
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein
Recently, α‐synuclein was shown to be a structural component of the filaments in Lewy bodies (LBs) of Parkinson's disease (PD… 
Highly Cited
1960
Highly Cited
1960
CHONDROGENESIS, STUDIED WITH THE ELECTRON MICROSCOPE
The role of the cells in the fabrication of a connective tissue matrix, and the structural modifications which accompany… 
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