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Cytochrome p450 CYP2B6 enzyme

Known as: 1,4 Cineole 2 exo Monooxygenase, Cytochrome P 450 CYP2B6, P450 2B6, Cytochrome 
A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is… 
National Institutes of Health

Papers overview

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2008
2008
Background: Interpatient variability in efavirenz concentrations may be due to CYP2B6 genetic polymorphisms. Efavirenz… 
2008
2008
[3H]Cimetidine (3HCIM) specifically binds to an unidentified site in the rat brain. Because recently described ligands for this… 
2007
2007
Objectives CYP2A6 is the major enzyme involved in nicotine metabolism, yet large interindividual variations in the rate of… 
Highly Cited
2005
Highly Cited
2005
Nornicotine is an N-demethylated metabolite of nicotine. In the present study, human cytochrome P450 (P450) isoform(s) involved… 
2003
2003
Animals treated with multiple doses of bupropion have had increased bupropion clearance or increased liver weight, suggesting… 
Highly Cited
2002
Highly Cited
2002
Tamoxifen is primarily used in the treatment of breast cancer. It has been approved as a chemopreventive agent for individuals at… 
Highly Cited
2001
Highly Cited
2001
In view of conflicting data in the literature regarding the enzyme(s) responsible for metabolism of selegiline, a drug used in…