Cytochrome p450 CYP2B6 enzyme

Known as: 1,4 Cineole 2 exo Monooxygenase, Cytochrome P 450 CYP2B6, P450 2B6, Cytochrome 
A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is… (More)

Topic mentions per year

Topic mentions per year

1995-2017
010203019952017

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Metabolism and clearance of racemic methadone are stereoselective and highly variable, yet the mechanism remains… (More)
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2007
2007
Organophosphorus pesticides (OPs) remain a potential concern to human health because of their continuing worldwide use… (More)
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2005
2005
The oxidative and conjugative metabolism of sertraline was examined in vitro to identify the enzymes involved in the generation… (More)
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Highly Cited
2004
Highly Cited
2004
The objectives of this study were to evaluate the ability of 14 compounds, which differentially activate human pregnane X… (More)
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Highly Cited
2003
Highly Cited
2003
Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450… (More)
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2003
2003
Cytochrome P450 (P450) 2B6 is a hepatic enzyme of potential importance for the metabolism of clinically used drugs and… (More)
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Highly Cited
2002
Highly Cited
2002
The interactions of a panel of antifungal agents with cytochromes P450 (P450s), as a means of predicting potential drug-drug… (More)
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Highly Cited
2000
Highly Cited
2000
The purpose of this study was to establish bupropion (BUP) hydroxylation as a selective in vitro marker of cytochrome P450 (CYP… (More)
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Highly Cited
2000
Highly Cited
2000
The in vitro biotransformation of bupropion to hydroxybupropion was studied in human liver microsomes and microsomes containing… (More)
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Highly Cited
1999
Highly Cited
1999
AIMS The study aimed to identify the specific human cytochrome P450 (CYP450) enzymes involved in the metabolism of artemisinin… (More)
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