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Cytochrome P-450 CYP2E1 Inducers

Known as: P450 CYP2E1 Inducers, CYP2E1 Inducers, P450, CYP2E1 Inducers 
Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2E1.
National Institutes of Health

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Papers overview

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2014
2014
Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure
Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive… 
Highly Cited
2013
Highly Cited
2013
Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
IntroductionThe cytochrome P450 (CYP) enzymes are a class of heme-containing enzymes involved in phase I metabolism of a large… 
Highly Cited
2013
Highly Cited
2013
Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK☆
Review
2012
Review
2012
The potential of RECK inducers as antitumor agents for glioma.
Reversion-inducing cysteine-rich protein with Kazal motifs (RECK), a tumor and metastasis suppressor gene, is critical for the… 
Highly Cited
2011
Highly Cited
2011
CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
The mechanisms by which alcohol causes cell injury are not clear. A major mechanism is the role of lipid peroxidation and… 
2011
2011
Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County
BackgroundThe purpose of this study was to evaluate the association of multi-genotype polymorphisms with the stepwise progression… 
Highly Cited
2010
Highly Cited
2010
Cross-species comparison of fluoxetine metabolism with fish liver microsomes.
Highly Cited
2008
Highly Cited
2008
Development and properties of HepG2 cells that constitutively express CYP2E1.
CYP2E1, a member of the cytochrome P450 family, is induced by ethanol. CYP2E1 activates many hepatotoxins to their reactive toxic… 
2006
2006
Association between metabolic gene polymorphisms and susceptibility to peripheral nerve damage in workers exposed to n-hexane: A preliminary study
Abstract Chronic exposure to n-hexane may result in peripheral neuropathy. 2,5-Hexanedione (2,5-HD) has been identified as a… 
2001
2001
CYP2E1-Dependent Toxicity and Up-Regulation of Antioxidant Genes
Induction of cytochrome P450 2E1 (CYP2E1) by ethanol appears to be one of the central pathways by which ethanol generates a state… 
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