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Cytochrome P-450 CYP2B1

Known as: BROD, Benzyloxyresorufin O Dealkylase, CYP2B1 
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (3)

Cytochrome P450OxidoreductaseSteroid Hydroxylases
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain
Highly Cited
2002
Highly Cited
2002
Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
Highly Cited
1998
Highly Cited
1998
An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy
Herpes simplex viruses type 1 (HSV-1) with an inactivated viral ribonucleotide reductase (Hsrr, ICP6) were designed to target… 
Highly Cited
1996
Highly Cited
1996
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver.
Highly Cited
1996
Highly Cited
1996
Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat.
Highly Cited
1996
Highly Cited
1996
Effects of canthaxanthin, astaxanthin, lycopene and lutein on liver xenobiotic-metabolizing enzymes in the rat.
1. The catalytic activities of several phase I and II xenobiotic-metabolizing enzymes and the immunochemical detection of P4501A… 
Highly Cited
1992
Highly Cited
1992
Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
Phenethyl isothiocyanate (PEITC), a constituent of cruciferous vegetables, has been shown to inhibit chemical carcinogenesis… 
Highly Cited
1988
Highly Cited
1988
Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities.
It has been reported that p.o. administration of diallyl sulfide (DAS), a naturally occurring component of garlic (Allium sativum… 
Highly Cited
1983
Highly Cited
1983
High-affinity nitrosamine dealkylase system in rat liver microsomes and its induction by fasting.
In order to elucidate the enzymic basis of nitrosamine metabolism, the in vitro metabolism of nitrosamines by rat liver… 
Highly Cited
1950
Highly Cited
1950
Diurnal variations of renal function in man.
A diurnal rhythm in water and electrolyte excretion in man has been described by several investigators. Kleitman (1) reported… 
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