Cystinuria

Known as: High urine cystine levels, Cystinurias, CSNU1, FORMERLY 
An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Mammalian target of rapamycin (mTOR) is a protein kinase of the PI3K/Akt signaling pathway. Activation of mTOR in response to… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Carfilzomib (formerly PR-171) is a novel proteasome inhibitor of the epoxyketone class that is selective and structurally… (More)
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Highly Cited
2007
Highly Cited
2007
Nilotinib, an orally bioavailable, selective Bcr-Abl tyrosine kinase inhibitor, is 30-fold more potent than imatinib in pre… (More)
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Highly Cited
2005
Highly Cited
2005
Bortezomib (formerly PS-341) has significant activity in patients with relapsed multiple myeloma (MM), its efficacy is increased… (More)
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Review
2003
Review
2003
Bortezomib (formerly PS-341), a promising new drug for the treatment of multiple myeloma, recently received accelerated approval… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Chronic myelogenous leukemia (CML) is caused by the BCR-ABL tyrosine kinase, the product of the Philadelphia… (More)
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Highly Cited
2002
Highly Cited
2002
Chronic myelogenous leukemia (CML) is caused by expression of the BCR-ABL tyrosine kinase oncogene, the product of the t(9;22… (More)
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Highly Cited
2002
Highly Cited
2002
Recent developments in the genetics and physiology of cystinuria do not support the traditional classification, which is based on… (More)
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Highly Cited
1999
Highly Cited
1999
Cystinuria (MIM 220100) is a common recessive disorder of renal reabsorption of cystine and dibasic amino acids. Mutations in… (More)
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Highly Cited
1994
Highly Cited
1994
Cystinuria is a classic heritable aminoaciduria that involves the defective transepithelial transport of cystine and dibasic… (More)
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