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Cystathionine Beta-Synthase, human
Known as:
Serine Sulfhydrase
, EC 4.2.1.22
, Cystathionine Beta-Synthase
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Cystathionine beta-synthase (551 aa, ~61 kDa) is encoded by the human CBS gene. This protein plays a role in homocysteine metabolism.
National Institutes of Health
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Related topics
Related topics
10 relations
Amino Acid Biosynthesis
CBS gene
Catabolic Process
Cell Nucleus
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Broader (1)
Cystathionine beta-Synthase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.
S. Elshazly
,
M. El-Moselhy
,
W. Barakat
European Journal of Pharmacology
2014
Corpus ID: 2772018
Highly Cited
2008
Highly Cited
2008
Inhibition of cystathionine-beta-synthase activity during renal ischemia-reperfusion: role of pH and nitric oxide.
G. Prathapasinghe
,
Y. Siow
,
Zhibin Xu
,
K. O
AJP - Renal Physiology
2008
Corpus ID: 10306477
Our recent study (Prathapasinghe GA, Siow YL, O K. Am J Physiol Renal Physiol 292: F1354-F1363, 2007) indicates that homocysteine…
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Review
2006
Review
2006
Biochemistry of homocysteine in health and diseases.
S. Ramakrishnan
,
K. Sulochana
,
Soundarajan Lakshmi
,
R. Selvi
,
N. Angayarkanni
Indian Journal of Biochemistry & Biophysics
2006
Corpus ID: 28759043
The amino acid homocysteine (Hcy), formed from methionine has profound importance in health and diseases. In normal circumstances…
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Highly Cited
2006
Highly Cited
2006
Hyperhomocysteinemia inhibits post-injury reendothelialization in mice.
Hongmei Tan
,
Xiaohua Jiang
,
+7 authors
Hong Wang
Cardiovascular Research
2006
Corpus ID: 34134847
Review
2003
Review
2003
Reaction mechanism and regulation of cystathionine beta-synthase.
R. Banerjee
,
R. Evande
,
O. Kabil
,
S. Ojha
,
S. Taoka
Biochimica et Biophysica Acta
2003
Corpus ID: 601332
In mammals, cystathionine beta-synthase catalyzes the first step in the transsulfuration pathway which provides an avenue for the…
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2002
2002
The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats.
V. Fonseca
,
M. Keebler
,
+4 authors
D. B. McNamara
Metabolism: Clinical and Experimental
2002
Corpus ID: 26280022
We studied the effect of troglitazone on the plasma concentrations of homocysteine (tHcy), the erythrocyte and hepatic…
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Review
2002
Review
2002
Gene Polymorphism and Coronary Risk Factors in Indian Population
T. Ashavaid
,
K. Shalia
,
A. Kondkar
,
Seema P. Todur
,
K. G. Nair
,
S. Nair
Clinical Chemistry and Laboratory Medicine
2002
Corpus ID: 24126383
Abstract Asian Indians who have settled overseas and those in urban India have increased risk of coronary events. Reasons for…
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Highly Cited
2001
Highly Cited
2001
Functional Properties of the Active Core of Human Cystathionine β-Synthase Crystals*
S. Bruno
,
F. Schiaretti
,
P. Burkhard
,
J. Kraus
,
M. Janošík
,
A. Mozzarelli
Journal of Biological Chemistry
2001
Corpus ID: 26965315
Human cystathionine β-synthase is a pyridoxal 5′-phosphate enzyme containing a heme binding domain and anS-adenosyl-l-methionine…
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2000
2000
Characterization of the heme in human cystathionine beta-synthase by X-ray absorption and electron paramagnetic resonance spectroscopies.
S. Ojha
,
J. Hwang
,
O. Kabil
,
J. Penner‐Hahn
,
R. Banerjee
Biochemistry
2000
Corpus ID: 11850669
Human cystathionine beta-synthase is one of two key enzymes involved in intracellular metabolism of homocysteine. It catalyzes a…
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1990
1990
Early signs of vascular disease in homocystinuria: a noninvasive study by ultrasound methods in eight families with cystathionine-beta-synthase deficiency.
P. Rubba
,
F. Faccenda
,
+7 authors
G. Andria
Metabolism: Clinical and Experimental
1990
Corpus ID: 21349985
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