Cystathionine Beta-Synthase, human

Hydrogen sulfide (H(2)S) is a synaptic modulator as well as a neuroprotectant. Currently, pyridoxal-5'-phosphate (PLP)-dependent… Expand

•  Introduction •  Reactive nitrogen species (RNS) in the heart and vasculature •  (H2S) biosynthesis •  H2S measurement… Expand

Hydrogen sulfide is an endogenous mediator that relaxes vascular smooth muscle, exhibits several antiinflammatory activities, and… Expand

The transsulfuration pathway converts homocysteine to cysteine and represents the metabolic link between antioxidant and… Expand

Although hyperhomocysteinemia is an independent risk factor for cardiovascular disease, a direct role for homocysteine (Hcy) in… Expand

BACKGROUND & AIMS Low folate intake may increase risk for colorectal cancer by inducing DNA hypomethylation. This study reports… Expand

Although hydrogen sulfide (H2S) is generally thought of in terms of a poisonous gas, it is endogenously produced in the brain… Expand

Cystathionine β‐synthase (CBS) is a unique heme‐ containing enzyme that catalyzes a pyridoxal 5′‐phosphate (PLP)‐dependent… Expand

Mild hyperhomocysteinaemia is a major risk factor for vascular disease and neural tube defects (NTDs), conferring an… Expand

Using an in vitro system which contained enzymes, substrates, and other reactants at concentrations which approximated the in… Expand