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Cycloserine

Known as: D-(+)-Cycloserine, R-4-Amino-3-isoxazolidinone, alpha-Cycloserine 
An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall… 
National Institutes of Health

Related topics

Related topics

22 relations

Broader (4)

Anti-Infective Agents, UrinaryAntibiotics, AntitubercularAntimetabolitesSerine
Antimycobacterial drug poisoningCycloserine:MCnc:Pt:Ser/Plas:QnCycloserine:Susc:Pt:Isolate:OrdQnCycloserine:Susc:Pt:Isolate:Qn:MLC

Narrower (4)

OrientomycinPA 94Seromycinpentizidone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
d-serine enhances extinction of auditory cued fear conditioning via ERK1/2 phosphorylation in mice
2008
2008
Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats
Highly Cited
1996
Highly Cited
1996
Induction of glucosylceramide synthase by synthase inhibitors and ceramide.
Highly Cited
1989
Highly Cited
1989
Alanine is a major end product of metabolism by Giardia lamblia: a proton nuclear magnetic resonance study.
Highly Cited
1984
Highly Cited
1984
Computer-aided strategies for archive retrieval and sensitivity enhancement in the identification of drugs by photodiode array detection in high-performance liquid chromatography.
1981
1981
Identification of the dnaQ gene product and location of the structural gene for RNase H of Escherichia coli by cloning of the genes.
By in vitro recombination we have constructed hybrid plasmids capable of complementing a conditional lethal mutator mutation… 
Highly Cited
1978
Highly Cited
1978
Factors affecting the transformation of Escherichia coli strain chi1776 by pBR322 plasmid DNA.
Highly Cited
1969
Highly Cited
1969
Isolation of spontaneous mutant strains of Pseudomonas putida.
Highly Cited
1965
Highly Cited
1965
ALANINE: CYCLOSERINE ANTAGONISM. VI. DEMONSTRATION OF D-ALANINE IN THE SERUM OF GUINEA PIGS AND MICE.
Discovered in 1954 (24), the antib?otic cycloserine (oxamycin, n-4-amino-3-isoxazolidinone) was soon dubbed an antibiotic paradox… 
Highly Cited
1959
Highly Cited
1959
Reversal of Cycloserine Inhibition by D-alanine.∗
  • G. Shockman
  • Proceedings of the Society for Experimental…
  • 1959
  • Corpus ID: 41064549
Summary D-alanine, but not L-alanine, competitively reverses the inhibitory action of cycloserine on S. faecalis cells that are… 
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