Skip to search formSkip to main contentSkip to account menu

Cycloheximide

Known as: 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-, Cicloheximide, Cycloheximide [Chemical/Ingredient] 
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (6)

4,alpha-diepi-streptovitacin AActidioneE-73, acetoxyl cycloheximide analogacetoxycycloheximide

Broader (7)

AntibioticsAntibiotics, AntifungalAntifungal AgentsPiperidones
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Elevated gene expression and production of interleukins 2, 4, 5, and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma.
Aberrant elevation of serum IgA and induction of murine IgA nephropathy following dietary exposure to the naturally occurring… 
1981
1981
Cycloheximide-induced phase shifting of circadian clock of Neurospora.
Cycloheximide (CHX), an inhibitor of cytosolic (80S) protein synthesis in eucaryotes, causes phase shifts of the circadian clock… 
1979
1979
Alterations in the processing of rat-liver ribosomal RNA caused by cycloheximide inhibition of protein synthesis.
Cycloheximide given in vivo at low doses (2--5 mg/kg body weight) causes within 30 min a complete inhibition of protein synthesis… 
1978
1978
Cycloheximide resistance can be mediated through either ribosomal subunit.
Two cycloheximide-resistant mutants of Tetrahymena thermophila were analyzed to determine the site of their cycloheximide… 
1977
1977
Division delay after low X-ray doses and treatment with cycloheximide.
SCHNEIDERMAN, M. H., BRABY, L. A., AND ROESCH, W. C. Division Delay after Low X-Ray Doses and Treatment with Cycloheximide… 
Highly Cited
1976
Highly Cited
1976
Priming effect of luteinizing hormone releasing factor: in-vitro and in-vivo evidence consistent with its dependence upon protein and RNA synthesis.
The aim of this study was to determine whether the priming effect of LH-RF depends upon RNA and protein synthesis. In in-vivo… 
Highly Cited
1973
Highly Cited
1973
Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells.
1. A competitive binding assay was adapted for determination of the specific binding of glucocorticoids to cytoplasmic receptors… 
Highly Cited
1970
Highly Cited
1970
Mammalian cell-free protein synthesis directed by viral ribonucleic acid.
1 A cell-free system from mouse Krebs II ascites cells is described which responds by increased amino acid incorporation into… 
1967
1967
The effect of cycloheximide on tissue clearing-factor lipase activity.
The clearing-factor lipase activity of adipose tissue from fed rats has been shown to fall rapidly on starvation A rapid loss of… 
Highly Cited
1953
Highly Cited
1953
Use of cycloheximide medium for isolation of dermatophytes from clinical materials.
THE ISOLATION of dermatophytes from clinical materials frequently is complicated by contamination of culture tubes with bacteria…