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Cycloheximide

Known as: 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-, Cicloheximide, Cycloheximide [Chemical/Ingredient] 
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (6)

4,alpha-diepi-streptovitacin AActidioneE-73, acetoxyl cycloheximide analogacetoxycycloheximide

Broader (7)

AntibioticsAntibiotics, AntifungalAntifungal AgentsPiperidones
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells.
Highly Cited
1990
Highly Cited
1990
Identification of CRG-2. An interferon-inducible mRNA predicted to encode a murine monokine.
Highly Cited
1990
Highly Cited
1990
The regulation of tissue factor mRNA in human endothelial cells in response to endotoxin or phorbol ester.
Highly Cited
1986
Highly Cited
1986
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
Highly Cited
1983
Highly Cited
1983
Peroxisome proliferation in primary cultures of rat hepatocytes.
Highly Cited
1981
Highly Cited
1981
Energy-dependent and protein synthesis-independent recycling of the insulin-sensitive glucose transport mechanism in fat cells.
Highly Cited
1978
Highly Cited
1978
Evidence for a ninth influenza viral polypeptide.
Highly Cited
1976
Highly Cited
1976
Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein
Highly Cited
1972
Highly Cited
1972
Binding of cadmium ions by rat liver and kidney.
Highly Cited
1970
Highly Cited
1970
Specificity of cycloheximide in higher plant systems.
Although cycloheximide is extremely inhibitory to protein synthesis in vivo in higher plants, the reported insensitivity of some… 
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