Cycloheximide resistance can be mediated through either ribosomal subunit.

@article{Sutton1978CycloheximideRC,
  title={Cycloheximide resistance can be mediated through either ribosomal subunit.},
  author={Claudia A. Sutton and Manuel Ares and Richard L. Hallberg},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1978},
  volume={75 7},
  pages={3158-62}
}
Two cycloheximide-resistant mutants of Tetrahymena thermophila were analyzed to determine the site of their cycloheximide resistance. The mutations in both strains had been previously shown to be genetically dominant and located at separate loci (denoted Chx-A and Chx-B). Strains carrying these mutations were readily distinguished by the extent to which… CONTINUE READING