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Cyclin C

Known as: Cyclins, Type C, Type C Cyclin, Type C Cyclins 
A cyclin subtype that binds to the CYCLIN-DEPENDENT KINASE 3 and CYCLIN-DEPENDENT KINASE 8. Cyclin C plays a dual role as a transcriptional regulator… 
National Institutes of Health

Related topics

Related topics

20 relations
CCNC geneCell Cycle ControlCell NucleusGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Synergistic repression of thyroid hyperplasia by cyclin C and Pten
ABSTRACT The cyclin C–Cdk8 kinase has been identified as both a tumor suppressor and an oncogene depending on the cell type. The… 
2012
2012
Leukemogenesis as a new approach to investigate the correlation between up regulated gene 4/upregulator of cell proliferation (URG4/URGCP) and signal transduction genes in leukemia
The aim of the study is to the determine the profiles of cell cycle genes and a new candidate oncogene of URG4/URGCP which play… 
2006
2006
Genetic expression profiles and chromosomal alterations in sporadic breast cancer in Mexican women.
2006
2006
Osmosensitive gene expression of taurine transporter and cyclin C in embryonic fibroblast cells.
Hypertonic conditions induce osmoregulatory activity. Molecular mechanism, however, remains to be further elucidated concerning… 
2003
2003
Cyclin C expression is involved in the pathogenesis of Alzheimer’s disease
Highly Cited
1999
Highly Cited
1999
The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression.
The mediator complex is essential for regulated transcription in vitro. In the yeast Saccharomyces cerevisiae, mediator comprises… 
1998
1998
Functional cooperation of cyclin C and c-Myc in mediating homotypic cell adhesion via very late antigen-4 activation and vascular cell adhesion molecule-1 induction.
Very late antigen-4 (VLA-4)/vascular cell adhesion molecule-1 (VCAM-1) are a pair of adhesion molecules mediating cell-cell… 
Highly Cited
1996
Highly Cited
1996
Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II.
A number of cyclins have been described, most of which act together with their catalytic partners, the cyclin-dependent kinases… 
1996
1996
Alternatively spliced cyclin C mRNA is widely expressed, cell cycle regulated, and encodes a truncated cyclin box.
The cyclin C protein has recently been shown to associate with a unique cyclin dependent protein kinase (cdk8) and it has been… 
Review
1996
Review
1996
The cyclin C/Cdk8 kinase.
Cyclin C was originally identified in a genetic screen for metazoan cDNAs that complement a triple knock-out of the CLN genes… 
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