Cyclin A1

Known as: Cyclin A1 [Chemical/Ingredient], Cyclin-A1 
Cyclin-A1 (465 aa, ~52 kDa) is encoded by the human CCNA1 gene. This protein is involved in the G1/S and G2/M cell cycle transitions.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Interleukin-6 (IL6) is a growth and survival factor in human prostate cancer (PCa) cells with aggressive phenotypes and has been… (More)
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Highly Cited
2006
Highly Cited
2006
Methylation profiling of cancer tissues has identified this mechanism as an important component of carcinogenesis. Epigenetic… (More)
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Highly Cited
2004
Highly Cited
2004
Homeobox genes constitute a large family of transcription factors that are essential during normal development and are often… (More)
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Highly Cited
2004
Highly Cited
2004
Aberrant promoter hypermethylation of tumor suppressor genes is proposed to be a common feature of primary cancer cells. We… (More)
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2004
2004
Vertebrates express two A-type cyclins; both associate with and activate the CDK2 protein kinase. Cyclin A1 is required in the… (More)
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1999
1999
Cyclin A1 differs from other cyclins in its highly restricted expression pattern. Besides its expression during spermatogenesis… (More)
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1999
1999
Human cyclin A1 is a newly cloned, tissue-specific cyclin that is prominently expressed in normal testis. In this study, we… (More)
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Highly Cited
1998
Highly Cited
1998
The mammalian A-type cyclin family consists of two members, cyclin A1 (encoded by Ccna1) and cyclin A2 (encoded by Ccna2). Cyclin… (More)
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Highly Cited
1996
Highly Cited
1996
In this paper, the existence of two A-type cyclins in the mouse is demonstrated. In the adult mouse, the expression of cyclin A1… (More)
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Highly Cited
1994
Highly Cited
1994
Early in the development of many animals, before transcription begins, any change in the pattern of protein synthesis is… (More)
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