Skip to search formSkip to main contentSkip to account menu

Cyclin A1

Known as: Cyclin A1 [Chemical/Ingredient], Cyclin-A1 
Cyclin-A1 (465 aa, ~52 kDa) is encoded by the human CCNA1 gene. This protein is involved in the G1/S and G2/M cell cycle transitions.
National Institutes of Health

Related topics

Related topics

14 relations
CCNA1 geneCell Cycle ControlCell NucleusGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Disrupted cell cycle arrest and reduced proliferation in corneal fibroblasts from GCD2 patients: a potential role for altered autophagy flux.
2011
2011
Human Papillomavirus's Physical State and Cyclin A1 Promoter Methylation in Cervical Cancer
Background: Cervical cancer is the second biggest cause of death among human female cancers. Human papillomavirus (HPV) is the… 
2005
2005
Cyclin A Is a c-Jun Target Gene and Is Necessary for c-Jun-induced Anchorage-independent Growth in RAT1a Cells*
Overexpression of c-Jun enables Rat1a cells to grow in an anchorage-independent manner. We used an inducible c-Jun system under… 
Highly Cited
2004
Highly Cited
2004
Elevated levels and distinct patterns of expression of A‐type cyclins and their associated cyclin‐dependent kinases in male germ cell tumors
Aberrant expression of several key regulators controlling the G1/S phase of the cell cycle has been implicated in human male germ… 
2003
2003
Elevated levels of cyclin A1 and A (A2) mRNA in acute myeloid leukaemia are associated with increased survival
Summary. Cyclin A (A2) and cyclin A1 are members of the G2 cyclins, which are involved in the control of G2/M and G1/S… 
Highly Cited
2001
Highly Cited
2001
Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1
A mammalian A-type cyclin, cyclin A1, is highly expressed in testes of both human and mouse and targeted mutagenesis in the mouse… 
2000
2000
Interaction of Xenopus Cdc2·Cyclin A1 with the Origin Recognition Complex*
The initiation of DNA replication in eukaryotes is regulated in a minimum of at least two ways. First, several proteins… 
2000
2000
The aberrant fusion proteins PML-RAR alpha and PLZF-RAR alpha contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia.
Cyclin A1 is a newly discovered cyclin that is overexpressed in certain myeloid leukemias. Previously, the authors found that the… 
Highly Cited
1999
Highly Cited
1999
c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression.
Cyclin A1 differs from other cyclins in its highly restricted expression pattern. Besides its expression during spermatogenesis… 
1998
1998
Cyclin A1 is predominantly expressed in hematological malignancies with myeloid differentiation
Cyclin A is a cell cycle regulatory protein that functions in mitotic and S phase control in mammalian cells. However, in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)