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Cullin 2 Protein

Known as: Cullin-2, Cullin Homolog 2, CUL-2 
Cullin-2 (745 aa, ~87 kDa) is encoded by the human CUL2 gene. This protein is involved in both cell cycle regulation and protein ubiquitination.
National Institutes of Health

Related topics

Related topics

10 relations
CUL2 geneCullin Family ProteinGenes, RegulatorHomo sapiens

Papers overview

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2014
2014
Cellular Requirements for Bovine Immunodeficiency Virus Vif-Mediated Inactivation of Bovine APOBEC3 Proteins
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) viral infectivity factor (Vif) form… 
2014
2014
Distinctive EPR signals provide an understanding of the affinity of bis-(3-hydroxy-4-pyridinonato) copper(II) complexes for hydrophobic environments.
In this work we report the synthesis and characterization of a set of 3-hydroxy-4-pyridinone copper(ii) complexes with variable… 
2013
2013
Role of the CRL2LRR-1 E3 ubiquitin-ligase in the development of the germline in C. elegans
The ubiquitin-proteolytic system (UPS) regulates a variety of cellular and biological processes by controlling the stability of… 
2012
2012
Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila
Cullins confer substrate specificity to E3-ligases which are multi-protein complexes involved in ubiquitin-mediated protein… 
2010
2010
C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues.
2006
2006
The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta.
The VHL (von Hippel-Lindau) tumour-suppressor protein forms a multi-protein complex [VCB (pVHL-elongin C-elongin B)-Cul-2 (Cullin… 
2005
2005
Caenorhabditis elegans Elongin BC complex is essential for cell proliferation and chromosome condensation and segregation during mitosis and meiotic division II
The ubiquitin-mediated protein degradation system is involved in a wide variety of cellular functions. The RING-H2 finger protein… 
2003
2003
Potentiometric studies on the stability constants of some a-amino acid-copper(II) and nickel(II) systems in ethanol-water mixture
The stability constants for the nickel(II) and copper(II)-α-amino acid (glycine, L-alanine, L-valine, L-leucine, L-isoleucine, L… 
2002
2002
Cobalt- and nickel-binding property of cullin-2.
Treatment with divalent metal ions such as cobalt (Co(2+)) or nickel (Ni(2+)) result in the stabilization of hypoxia-inducible… 
1999
1999
The von Hippel-Lindau Tumor Suppressor Gene Product Promotes, but Is Not Essential for, NEDD8 Conjugation to Cullin-2*
We have previously shown that human cullin-2 (Cul-2) is covalently modified at Lys-689 by NEDD8 (Wada, H., Yeh, E. T. H., and… 
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