Cryopyrin-Associated Periodic Syndromes

Known as: Cryopyrin-Associated Periodic Syndrome, Cryopyrin Associated Periodic Syndromes, CAPS 
A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ… (More)
National Institutes of Health

Related topics

Related topics

12 relations
Autoimmune DiseasesHereditary DiseasesIn BloodMicrobiological
(More)

Narrower (4)

Chronic Infantile Neurological, Cutaneous, and Articular SyndromeFamilial Cold Autoinflammatory Syndrome 2Familial cold urticariaMuckle-Wells Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS).
Cryopyrin-associated periodic syndrome (CAPS) is a rare, heterogeneous disease entity associated with NLRP3 gene mutations and… (More)
Is this relevant?
2011
2011
Bridging the gap between the clinician and the patient with cryopyrin-associated periodic syndromes.
Cryopyrin-associated periodic syndromes are categorized as a spectrum of three autoinflammatory diseases, namely familial cold… (More)
Is this relevant?
2010
2010
Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1beta secretion.
In healthy monocytes, Toll-like receptor (TLR) engagement induces production of reactive oxygen species (ROS), followed by an… (More)
Is this relevant?
Review
2010
Review
2010
Cryopyrin-associated periodic syndromes: background and therapeutics.
Cryopyrin-associated periodic syndromes (CAPS) are caused by mutations of the gene encoding the NLR family protein NLRP3, which… (More)
  • figure 1
  • table 1
  • table 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Use of canakinumab in the cryopyrin-associated periodic syndrome.
BACKGROUND The cryopyrin-associated periodic syndrome (CAPS) is a rare inherited inflammatory disease associated with… (More)
  • table 1
  • figure 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes
The investigation of interleukin 1beta (IL-1beta) in human inflammatory diseases is hampered by the fact that it is virtually… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Fungal zymosan and mannan activate the cryopyrin inflammasome.
Some fungal species are opportunistic pathogens that can cause infection in people with compromised immune systems. Activation of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2007
Review
2007
Cryopyrin-associated periodic syndromes and autoinflammation.
Autoinflammatory syndromes are a distinct class of inherited diseases of cytokine dysregulation with important cutaneous features… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Cryopyrin activates the inflammasome in response to toxins and ATP
A crucial part of the innate immune response is the assembly of the inflammasome, a cytosolic complex of proteins that activates… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Gout-associated uric acid crystals activate the NALP3 inflammasome
Development of the acute and chronic inflammatory responses known as gout and pseudogout are associated with the deposition of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?