Biomarkers in systemic juvenile idiopathic arthritis: a comparison with biomarkers in cryopyrin-associated periodic syndromes.

@article{Nirmala2014BiomarkersIS,
  title={Biomarkers in systemic juvenile idiopathic arthritis: a comparison with biomarkers in cryopyrin-associated periodic syndromes.},
  author={N. R. Nirmala and Alexei A. Grom and Hermann Gram},
  journal={Current opinion in rheumatology},
  year={2014},
  volume={26 5},
  pages={
          543-52
        }
}
PURPOSE OF REVIEW This review summarizes biomarkers in systemic juvenile idiopathic arthritis (sJIA). Broadly, the markers are classified under protein, cellular, gene expression and genetic markers. We also compare the biomarkers in sJIA to biomarkers in cryopyrin-associated periodic syndrome (CAPS). RECENT FINDINGS Recent publications showing the similarity of clinical response of sJIA and CAPS to anti-interleukin 1 therapies prompted a comparison at the biomarker level. SUMMARY sJIA… CONTINUE READING
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