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Compound Q

Known as: alpha-Trichosanthin, Trichosanthin [Chemical/Ingredient], Proteins, specific or class, trichosanthins 
Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Abortifacient Agents, NonsteroidalAnti-HIV AgentsAntineoplastic Agents, Phytogenic

Narrower (1)

GLQ-223
In BloodProcess of secretionTrichosanthisagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Antitumor effects of curcin from seeds of Jatropha curcas.
AIM To study the antitumor effects of curcin from Jatropha curcas. METHODS Antitumor activity of curcin was tested by MTT assay… 
Highly Cited
2001
Highly Cited
2001
Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells.
The type-I ribosome-inactivating protein trichosanthin (TCS) has a broad spectrum of biological and pharmacological activities… 
Highly Cited
2000
Highly Cited
2000
The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV‐1 integrase
Highly Cited
1999
Highly Cited
1999
Anti-HIV Agent Trichosanthin Enhances the Capabilities of Chemokines to Stimulate Chemotaxis and G Protein Activation, and This Is Mediated through Interaction of Trichosanthin and Chemokine…
Trichosanthin (TCS), an active protein component isolated from a traditional Chinese medicinal herb Trichosanthes kirilowii, has… 
Highly Cited
1993
Highly Cited
1993
Rapid, high-level expression of biologically active alpha-trichosanthin in transfected plants by an RNA viral vector.
alpha-Trichosanthin, a eukaryotic ribosome-inactivating protein from Trichosanthes kirilowii, inhibits the replication of the… 
Highly Cited
1993
Highly Cited
1993
Ebulin 1, a nontoxic novel type 2 ribosome-inactivating protein from Sambucus ebulus L. leaves.
Review
1992
Review
1992
Proteins with abortifacient, ribosome inactivating, immunomodulatory, antitumor and anti-AIDS activities from Cucurbitaceae plants.
Highly Cited
1992
Highly Cited
1992
The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin.
Trichosanthin is a ribosome-inactivating protein from root tubers of Trichosanthes kirilowii Maxim. In this paper, the mechanism… 
Highly Cited
1989
Highly Cited
1989
GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage.
GLQ223 is a highly purified, formulated preparation of trichosanthin, a 26-kDa plant-derived ribosome-inactivating protein with… 
Highly Cited
1989
Highly Cited
1989
Ribosome inactivation by ricin A chain: a sensitive method to assess the activity of wild‐type and mutant polypeptides.
When recombinant ricin A chain transcripts are translated in a rabbit reticulocyte lysate the ribosomes are rapidly inactivated… 
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